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Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML
Authors: Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela Wenge, Florian Perner, Cynthia Martucci, Jill A Henrich, Kelly Klega, Radoslaw P Nowak, Katherine Aleisha Donovan, Meaghan Boileau, Yanhe Wen, Charles Hatton, Athina A Apazidis, Sarah N Olsen, Nadia Kirmani, Yana Pikman, Jessica A Pollard, Jennifer A Perry, Adam S Sperling, Benjamin L Ebert, Gerard M McGeehan, Brian D Crompton, Eric S Fischer, Scott A Armstrong
Journal: Blood
PubMed ID: 38096371
Doi: 10.1182/blood.2023021105
Products & Services: Peptide Synthesis   
Bioinformatics analyses of infiltrating immune cell participation on pancreatic ductal adenocarcinoma progression and in vivo experiment of the therapeutic effect of Shuangshen granules
Authors: Jiaqi Hu, Juling Jiang, Bowen Xu, Yue Li, Bei Wang, Shulin He, Xiaoling Ren, Bolun Shi, Xing Zhang, Honggang Zheng, Baojin Hua, Rui Liu
Journal: J Ethnopharmacol
PubMed ID: 38113986
Doi: 10.1016/j.jep.2023.117590
Products & Services: Proteins, Expression, Isolation and Analysis   
Acid phosphatase-like proteins, a biogenic amine and leukotriene-binding salivary protein family from the flea Xenopsylla cheopis
Authors: Stephen Lu, John F Andersen, Christopher F Bosio, B Joseph Hinnebusch, José M Ribeiro
Journal: Commun Biol
PubMed ID: 38110569
Doi: 10.1038/s42003-023-05679-0
Products & Services: Recombinant Proteins   
Agonistic Bivalent Human scFvs-Fcγ Fusion Antibodies to OX40 Ectodomain Enhance T Cell Activities against Cancer
Authors: Kodchakorn Mahasongkram, Kantaphon Glab-Ampai, Kanasap Kaewchim, Thanatsaran Saenlom, Monrat Chulanetra, Nitat Sookrung, Oytip Nathalang, Wanpen Chaicumpa
Journal: Vaccines (Basel)
PubMed ID: 38140230
Doi: 10.3390/vaccines11121826
Products & Services: Recombinant Proteins   
Efficient de novo production of bioactive cordycepin by Aspergillus oryzae using a food-grade expression platform
Authors: Sukanya Jeennor, Jutamas Anantayanon, Sarocha Panchanawaporn, Chanikul Chutrakul, Wanwipa Vongsangnak, Kobkul Laoteng
Journal: Microb Cell Fact
PubMed ID: 38071331
Doi: 10.1186/s12934-023-02261-5
Products & Services: Molecular Biology Reagents   
Resveratrol-derived inhibitors of the E3 ubiquitin ligase PELI1 inhibit the metastasis of triple-negative breast cancer
Authors: Guangsen Xu, Qian Zhou, Jie Qi, Zhongyue Li, Lijun Yin, Zhuoran Li, Chunhua Lu, Baobing Zhao, Yuemao Shen
Journal: Eur J Med Chem
PubMed ID: 38150964
Doi: 10.1016/j.ejmech.2023.116060
Products & Services: PCR Cloning and Subcloning   
Worsening of imiquimod-induced psoriasiform inflammation in mice by environmental pollutant, di-(2-ethylhexyl) phthalate through dysregulation in IL-17A and Nrf2/iNOS signaling in peripheral myeloid and CD4 + T cells
Authors: Ali S Alfardan, Ahmed Nadeem, Sheikh F Ahmad, Naif O Al-Harbi, Mohammed Alqinyah, Sabry M Attia, Wedad Sarawi, Ahmed Z Alanazi, Khalid Alhazzani, Khalid E Ibrahim
Journal: Int Immunopharmacol
PubMed ID: 38056199
Doi: 10.1016/j.intimp.2023.111293
Products & Services: PCR Cloning and Subcloning   
Ferricyanide-promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media
Authors: Guo-Chao Chu, Lu-Jun Liang, Rui Zhao, Yan-Yan Guo, Chun-Tong Li, Chong Zuo, Huasong Ai, Xiao Hua, Zi-Chen Li, Yi-Ming Li, Lei Liu
Journal: CCS Chemistry
Doi: 10.31635/ccschem.023.202303397
Products & Services: Proteins, Expression, Isolation and Analysis   
Immunoswitch Nanomodulators Enable Active Targeting and Selective Proliferation of Regulatory T Cells for Multiple Sclerosis Therapy
Authors: Xiaoshuang Wang , Zhilin Liu , Di Wang , Yingyu Zhang , Honglei Zhang , Fuxin Xue , Xianhong Wang , Zhaohui Tang , Xuemei Han
Journal: ACS Nano .
PubMed ID: 38113242
Doi: 10.1021/acsnano.3c09225
Products & Services: Catalog Peptides   
In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma
Authors: Qiang Cheng, Lukas Farbiak, Amogh Vaidya, Erick Guerrero, Eunice E Lee, Elysha K Rose, Xu Wang, Joshua Robinson, Sang M Lee, Tuo Wei, William E Miller, Ester Alvarez Benedicto, Xizhen Lian, Richard C Wang, Daniel J Siegwart
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38109533
Doi: 10.1073/pnas.2313009120
Products & Services: Proteins, Expression, Isolation and Analysis   

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