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Oral delivery of therapeutic proteins by engineered bacterial type zero secretion system

Authors: Xu Gong , Shan Liu , Bozhang Xia , Yichen Wan , Shuyi Zhang , Baoyan Zhang , Zehao Wang , Junge Chen , Fei Xiao , Xing-Jie Liang , Yun Yang

Journal: Nat Commun

PubMed ID: 39984501

Doi: 10.1038/s41467-025-57153-6

Products & Services: Gene Synthesis

Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors

Authors: Hudie Wei, Haolan Wang, Shuang Xiang, Jiaqi Wang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Xiaoyun Lu, Yongheng Chen

Journal: Cell Death Differ

PubMed ID: 39901037

Doi: 10.1038/s41418-025-01454-2

Products & Services: Peptide Synthesis

Double antibody sandwich ELISA based on rabbit monoclonal antibody targeting gD protein for the detection of bovine herpesvirus 1

Authors: Qiang Liu, Xiaoxia Niu, Lingling Jiang, Gang Zhang, Pu Wang, Sinong Zhang, Weifeng Gao, Huichen Guo, Yujiong Wang, Yong Li

Journal: Int J Biol Macromol

PubMed ID: 39929469

Doi: 10.1016/j.ijbiomac.2025.140671

Products & Services: Gene Synthesis

DNA tetrahedron nanomedicine for enhanced antitumor and antimetastatic effect through the amplification of mitochondrial oxidative stress

Authors: Zixuan Chen , Zhaoyan Tian , Yafeng Wu , Songqin Liu

Journal: Acta Biomater

PubMed ID: 39922515

Doi: 10.1016/j.actbio.2025.02.011

Products & Services: Proteins, Expression, Isolation and Analysis

Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK

Authors: Chang Peng, Haowen Jiang, Liya Jing, Wenhua Yang, Xiaotong Guan, Hanlin Wang, Sike Yu, Yutang Cao, Min Wang, Huan Ma, Zan Lv, Hongyu Gu, Chunmei Xia, Xiaozhen Guo, Bin Sun, Aili Wang, Cen Xie, Wenbiao Wu, Luyiyi Lu, Jiayi Song, Saifei Lei, Rui Wu, Yi Zang, Erjiang Tang, Jia Li

Journal: Nat Commun

PubMed ID: 39966410

Doi: 10.1038/s41467-025-57044-w

Products & Services: Peptide Synthesis

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins

Authors: Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M McAloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy

Journal: Proc Natl Acad Sci U S A

PubMed ID: 39964718

Doi: 10.1073/pnas.2420961122

Products & Services: Peptide Synthesis

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds

Authors: Jiani Lu、Yan Tang、Hongtao Li、Xixiang Chen、Pengcheng Qin、Jianrong Xu、Weihua Li 和 Lili Chen

Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Doi: doi.org/10.3390/ijms26052243

Products & Services: Plasmid DNA Preparation

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein

Authors: Qiang Liu , Xiaoxia Niu , Lingling Jiang , Gang Zhang , Pu Wang , Sinong Zhang , Weifeng Gao , Huichen Guo, Yujiong Wang and Yong Li

Journal: Frontiers in Veterinary Science

Doi: 10.3389/fvets.2025.1530870

Products & Services: Plasmid DNA Preparation

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