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Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen
Journal: Nat Commun
PubMed ID: 38740822
Doi: 10.1038/s41467-024-48481-0
Products & Services: Mutagenesis Services   
Diverse Combinatorial Biosynthesis Strategies for C–H Functionalization of Anthracyclinones
Authors: Rongbin Wang , Benjamin Nji Wandi , Nora Schwartz , Jacob Hecht , Larissa Ponomareva, Kendall Paige , Alexis West , Kathryn Desanti , Jennifer Nguyen , Jarmo Niemi , Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä , S Eric Nybo
Journal: ACS Synth Biol
PubMed ID: 38662967
Doi: doi.org/10.1021/acssynbio.4c00043
Products & Services: Gene Synthesis   PCR Cloning and Subcloning   PCR and Cloning   
Development of advanced control material for reverse transcription-mediated bacterial nucleic acid amplification tests
Authors: Janessa D Lewis , Stephen J Salipante
Journal: J Clin Microbiol
PubMed ID: 38629844
Doi: 10.1128/jcm.00243-24
Products & Services: Gene Synthesis   
CRISPR/Cas13a-based supersensitive circulating tumor DNA assay for detecting EGFR mutations in plasma
Authors: Li Wang , Xiaosha Wen , Yang Yang , Zheng Hu , Jing Jiang , Lili Duan , Xiaofen Liao , Yan He , Yaru Liu , Jing Wang , Zhikun Liang , Xiaoya Zhu , Quan Liu , Tiancai Liu , Dixian Luo
Journal: Commun Biol
PubMed ID: 38806596
Doi: 10.1038/s42003-024-06368-2
Products & Services: Plasmid DNA Preparation   
Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity
Authors: Min Wu, Guangping Song, Jianing Li, Zengqing Song, Bing Zhao, Liyun Liang, Wenlong Li, Huaibin Hu, Haiqing Tu, Sen Li, Peiyao Li, Biyu Zhang , Wen Wang, Yu Zhang , Wanpeng Zhang, Weifan Zheng, Jiarong Wang, Yuqi Wen, Kai Wang, Ailing Li, Tao Zhou, Yucheng Zhang, Huiyan Li
Journal: Cell
Doi: 10.1016/j.cell.2024.04.027
Products & Services: Catalog Peptides   
The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation
Authors: Joanne Saldanha , Julie Rageul , Jinal A Patel , Amy L Phi , Natalie Lo , Jennifer J Park , Hyungjin Kim
Journal: Nucleic Acids Res
PubMed ID: 38801073
Doi: 10.1093/nar/gkae445.
Products & Services: PCR Cloning and Subcloning   
Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes
Authors: Fleur Chapus 1, Guillaume Giraud 2, Pélagie Huchon 3, Mélanie Rodà 2, Xavier Grand 2, Caroline Charre 4, Chloé Goldsmith 5, Armando Andres Roca Suarez 2, Maria-Guadalupe Martinez 1, Judith Fresquet 6, Audrey Diederichs 3, Maëlle Locatelli 1, Hélène Polvèche 7, Caroline Scholtès 8, Isabelle Chemin 2, Hector Hernandez Vargas 5, Michel Rivoire 9, Cyril F Bourgeois 10, Fabien Zoulim 11, Barbara Testoni 12
Journal: J Hepatol
PubMed ID: 38782119
Doi: doi: 10.1016/j.jhep.2024.05.016.
Products & Services: Mutagenesis Services   
but not is the avirulence determinant in melon carrying the resistance against watermelon mosaic virus, although they contain a common genetic determinant
Authors: Zhen Sun, Yu-Xuan Wu, Ling-Zhi Liu, Yan-Ping Tian, Xiang-Dong Li, Chao Geng
Journal: J Virol
PubMed ID: 38775482
Doi: 10.1128/jvi.00507-24
Products & Services: Proteins, Expression, Isolation and Analysis   
Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir
Authors: Yunxia Xu, Yaqi Wu, Xiaoying Wu, Yuanyuan Zhang, Yaxue Yang, Danyang Li, Biao Yang, Kaiting Gao, Zhengyu Zhang, Changjiang Dong
Journal: Int J Biol Macromol
PubMed ID: 38735603
Doi: 10.1016/j.ijbiomac.2024.132231
Products & Services: Proteins, Expression, Isolation and Analysis   
Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study
Authors: Tomas O Jensen, Thomas A Murray, Greg A Grandits, Mamta K Jain, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko
Journal: Lancet Microbe
PubMed ID: 38815595
Doi: 10.1016/S2666-5247(24)00015-6
Products & Services: Serology SARS-Cov-2 detection kits   

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