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Alpha and gamma mangostins inhibit wild-type B SARS-CoV-2 more effectively than the SARS-CoV-2 variants and the major target is unlikely the 3C-like protease
Authors: Aphinya Suroengrit, Van Cao, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Ryuhei Harada, Supakarn Chamni, Asada Leelahavanichkul, Yasuteru Shigeta, Thanyada Rungrotmongkol, Supot Hannongbua, Warinthorn Chavasiri, Supaporn Wacharapluesadee, Eakachai Prompetchara, Siwaporn Boonyasuppayakorn
Journal: Heliyon
PubMed ID: 38867992
Doi: 10.1016/j.heliyon.2024.e31987
Products & Services: Serology SARS-Cov-2 detection kits   
Discovery of UMI-77 as a novel Ku70/80 inhibitor sensitizing cancer cells to DNA damaging agents in vitro and in vivo
Authors: Xuening Chen, Changkun Chen, Chengmiao Luo, Jianyong Liu, Zhonghui Lin
Journal: Eur J Pharmacol
PubMed ID: 38754534
Doi: 10.1016/j.ejphar.2024.176647
Products & Services: Molecular Biology Reagents   
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury
Authors: Yuhao Xu, Limoran Tang, Chao Zhou, Liang Sun, Yujie Hu, Zhi Zhang, Shengnan Xia, Xinyu Bao, Haiyan Yang, Yun Xu
Journal: CNS Neurosci Ther
PubMed ID: 38715283
Doi: 10.1111/cns.14742
Products & Services: Proteins, Expression, Isolation and Analysis   
YANK2 activated by Fyn promotes glioma tumorigenesis via the mTOR-independent p70S6K activation pathway
Authors: Yue Shi, Yue Cheng, Wei Wang, Liu Tang, Wensheng Li, Liyuan Zhang, Zheng Yuan, Feng Zhu, Qiuhong Duan
Journal: Sci Rep
PubMed ID: 38714727
Doi: 10.1038/s41598-024-61157-5
Products & Services: Proteins, Expression, Isolation and Analysis   
Functional Analysis of the Major Pilin Proteins of Type IV Pili in CGMH010
Authors: Yi-Ywan M Chen, Yuan-Chen Yang, Hui-Ru Shieh, Yu-Juan Lin, Wan-Ju Ke, Cheng-Hsun Chiu
Journal: Int J Mol Sci
PubMed ID: 38791440
Doi: 10.3390/ijms25105402
Products & Services: Gene Synthesis   
Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies
Authors: Roman R Schlimgen, Francis C Peterson, Raimond Heukers, Martine J Smit, John D McCorvy, Brian F Volkman
Journal: Nat Commun
PubMed ID: 38816420
Doi: 10.1038/s41467-024-49000-x
Products & Services: Molecular Biology Reagents   
Functional Characterization of F3H Gene and Optimization of Dihydrokaempferol Biosynthesis in
Authors: Qinyi Chen, Dandan Song, Xiaoyan Sun, Yulong Tian, Zecheng Yan, Ting Min, Hongxun Wang, Limei Wang
Journal: Molecules
PubMed ID: 38792058
Doi: 10.3390/molecules29102196
Products & Services: Codon Optimization   
SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses
Authors: Ze-Zheng Jiang, Min Chu, Li-Na Yan, Wen-Kang Zhang, Bang Li, Jiao Xu, Zhong-Xin Zhao, Hui-Ju Han, Chuan-Min Zhou, Xue-Jie Yu
Journal: Microbiol Spectr
PubMed ID: 38712963
Doi: 10.1128/spectrum.03796-23
Products & Services: Molecular Biology Reagents   
Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat
Authors: Yayu Chen, Gen Wei, Lieliang Zhang, Xiaojin Feng, Enjun Lei
Journal: Exp Neurol
PubMed ID: 38823674
Doi: 10.1016/j.expneurol.2024.114842
Products & Services: Gene Synthesis   
Semi-rational design for enhancing thermostability of Culex pipiens acetylcholinesterase and sensitivity analysis of acephate
Authors: Shuoqi Jiang, Zhuangwei Zhang, Qiuya Gu, Xiaobin Yu
Journal: Sci Total Environ
PubMed ID: 38759926
Doi: 10.1016/j.scitotenv.2024.173282
Products & Services: Proteins, Expression, Isolation and Analysis   

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