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Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction

Authors: Xinming Wang, Yiming Zhong, Bei Qian, Shixing Huang, Qiang Long, Haonan Zhang, Qiang Zhao, Xiaofeng Ye

Journal: Materials today, Bio

PubMed ID: 40893381

Doi: 10.1016/j.mtbio.2025.102205

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A Novel Fluorescence Polarization Binding Assay for the Main Protease (M pro ) of SARS-CoV 2

Authors: Mackenzie K. Wyllie; Rayhan G. Biswas; Jyoti Vishwakarma; Morgan A. Esler; Joseph A. Rollie; Hideki Aihara; Reuben S. Harris; Daniel A. Harki

Journal: ACS pharmacology & translational science

PubMed ID: 41262570

Doi: 10.1021/acsptsci.5c00463

Identification of 14-3 3 Proteins as Binding Partners of TRP Channels

Authors: Nicol s Pe a-Vilches; Mariela Gonz lez-Avenda o; Nicole Soto-Garc a; Diego Maureira; Ian Silva; Javiera Avil s; El as Manr quez-Ben tez; Exequiel Medina; Oscar Cerda; Pablo Galaz-Davison; Ariela Vergara-Jaque

Journal: Journal of chemical information and modeling

PubMed ID: 41839059

Doi: 10.1021/acs.jcim.6c00092

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602

Doi: 10.1038/s41467-025-62303-x.

Products & Services: Polyclonal Antibody Services

GTP hydrolysis triggers membrane remodeling by AMPH-1

Authors: Wei Gai https://orcid.org/0009-0005-5681-7380, Yuhang Wang https://orcid.org/0000-0002-8048-138X, Brianna Martin, Junjie Zhang https://orcid.org/0000-0002-7912-0819, Chavela M. Carr https://orcid.org/0009-0005-1292-1119, and Hays S. Rye

Journal: SCIENCE ADVANCES

PubMed ID: 40749062

Doi: 10.1126/sciadv.ads9443

Products & Services: Protein and Antibody Isolation

The EMC acts as a chaperone for membrane proteins

Authors: Carolin J Klose, Kevin M Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J Feige

Journal: Nature Communications

PubMed ID: 40753078

Doi: 10.1038/s41467-025-62109-x

Products & Services: Catalog Antibodies

Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang

Journal: Nature Communications

PubMed ID: 40759657

Doi: 10.1038/s41467-025-62506-2

Products & Services: Custom DNA/RNA Oligos

Exomeres From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promote Vascular Remodelling via Transferring Osteopontin.

Authors: Jing-Xiao Wang, Xiao-Yu Xu, Hong-Ke Dong, Yi-Ming Wang, Min Dai, Bing Zhou, Yue-Hua Li, Guo-Qing Zhu, Xiao-Qing Xiong

Journal: Journal of extracellular vesicles

PubMed ID: 40767027

Doi: 10.1002/jev2.70146.

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The Heme Oxygenase-Like Diiron Enzyme HrmI Reveals Altered Regulatory Mechanisms for Dioxygen Activation and Substrate N-Oxygenation

Authors: Sydney S Skirboll, Medha Gangopadhyay, Han N Phan, Joshua Hartsell, Aditi Mudireddy, Dalton Hilovsky, Paul D Swartz, Xiaojing Liu, Yisong Guo, Thomas M Makris

Journal: Journal of the American Chemical Society

PubMed ID: 40774922

Doi: doi.org/10.1021/jacs.5c08814

Products & Services: Gene Synthesis