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Dual inhibition of DNA-PK and Polϴ boosts precision of diverse prime editing systems
Authors: Louis C Dacquay, Panagiotis Antoniou, Astrid Mentani, Niklas Selfjord, Hanna Mårtensson, Pei-Pei Hsieh, Salman Mustfa, George Thom, Sandra Wimberger, Mike Firth, Nina Akrap, Marcello Maresca, Martin Peterka
Journal: Nature Communications
PubMed ID: 40341582
Doi: 10.1038/s41467-025-59708-z
Products & Services: Gene Synthesis   
DDX3 Regulates the Cap-Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome
Authors: Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming-An Sun, Yanhua Li
Journal: Advanced Science
PubMed ID: 40344524
Doi: 10.1002/advs.202502493
C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening
Authors: Guiyou Tian, Lirong Huang, Zhaopeng Xu, Chen Lu, Wei Yuan, Yulin Wu, Zhipeng Liao, Jia Gao, Qiang Luo, Bo Cheng, Xinjun Liao, Huiqiang Lu
Journal: SCIENCE ADVANCES
PubMed ID: 40344050
Doi: 10.1126/sciadv.adv2032
Products & Services: Gene Synthesis   
Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
Authors: Wen-Hao Han, Feng-Bin Zhang, Shun-Xia Ji, Kai-Lu Liang, Jun-Xia Wang, Xiao-Ping Fan, Shu-Sheng Liu, Xiao-Wei Wang
Journal: SCIENCE ADVANCES
PubMed ID: 40344064
Doi: 10.1126/sciadv.adu5141
Products & Services: Gene Synthesis   
Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair
Authors: F Li, A S Phadte, M Bhatia, S Barndt, A R Monte Carlo Iii, C-F D Hou, R Yang, S Strock, A Pluciennik
Journal: Nature Communications
PubMed ID: 40368897
Doi: 10.1038/s41467-025-59323-y
Products & Services: Mutagenesis Services   
Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP
Authors: Justin M Waldern, Colin Taylor, Catherine A Giannetti, Patrick S Irving, Scott R Allen, Mingyi Zhu, Rolf Backofen, Dave Mathews, Kevin M Weeks, Alain Laederach
Journal: Nucleic Acids Research
PubMed ID: 39713457
Doi: 10.1101/2024.12.13.628372
Products & Services: Gene Synthesis   
FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma
Authors: Michal Beffinger, Linda Schellhammer, Betül Taskoparan, Sereina Deplazes, Ulisse Salazar, Nazanin Tatari, Frauke Seehusen, Leopold von Balthazar, Carl Philipp Zinner, Sabine Spath, Tala Shekarian, Marie-Françoise Ritz, Marta McDaid, Pascal Egloff, Iwan Zimmermann, Hideho Okada, E Sally Ward, Jack Rohrer, Markus A Seeger, Thorsten Buch, Gregor Hutter, Johannes Vom Berg
Journal: Nature Communications
PubMed ID: 40404625
Doi: 10.1038/s41467-025-59971-0
Products & Services: Protein Electrophoresis and Western   
The ALX4 dimer structure provides insight into how disease alleles impact function
Authors: Brittany Cain , Zhenyu Yuan , Evelyn Thoman, Rhett A Kovall , Brian Gebelein
Journal: Nature Communications
PubMed ID: 40410151
Doi: 10.1038/s41467-025-59728-9
Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease
Authors: Meng Jiang, Qingqing Li, Jianhui Chen, Ruochong Li, Jun Yao, Yong Hu, Haizheng Zhang, Lixin Cai, Maoguo Luo, Yu Sun, Wenwen Zeng
Journal: Advanced Science
PubMed ID: 40349168
Doi: 10.1002/advs.202417733
Products & Services: Protein and Antibody Isolation   
HR eye & MMR eye: one-day assessment of DNA repair-defective tumors eligible for targeted therapy
Authors: Shinta Saito, Shingo Kato, Usaki Arai, Atsuki En, Jun Tsunezumi, Taichi Mizushima, Kensuke Tateishi, Noritaka Adachi
Journal: Nature Communications
PubMed ID: 40355434
Doi: 10.1038/s41467-025-59462-2
Products & Services: Gene Synthesis   
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