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Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair

Authors: Nourisson Antonin , Missoury Sophia, Lucas-Staat Soizick , Haouz Ahmed , Delarue Marc

Journal: Nucleic Acids Research

PubMed ID: 40829804

Doi: 10.1093/nar/gkaf786

Products & Services: Gene Synthesis

Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis

Authors: Emma Schuster, Nurmaa K Dashzeveg, Fangjia Tong, Yuzhi Jia, Lamiaa El-Shennawy, Tong Zhang, Andrew D Hoffman, Reta Birhanu Kitata, Golam Kibria, Youbin Zhang, Joshua R Squires, Chunlei Zheng, Erika Ramos, Rokana Taftaf, David Scholten, Hannah F Almubarak, Valery Adorno-Cruz, David P Sullivan, Carolina Reduzzi, Allegra C Minor, William Purev-Ochir, Sabina Spahija, Rong Xu, Kalliopi P Siziopikou, Leonidas C Platanias, Ami Shah, William A Muller, William J Gradishar, Massimo Cristofanilli, Chia-Feng Tsai, Tujin Shi, Huiping Liu

Journal: Nature Communications

PubMed ID: 40818975

Doi: 10.1038/s41467-025-62862-z

Products & Services: Custom Vector Construction

Serological proteomic characterization for monitoring liver fibrosis regression in chronic hepatitis B patients on treatment

Authors: Mengyang Zhang, Shuyan Chen, Xiaoning Wu, Jialing Zhou, Bingqiong Wang, Tongtong Meng, Rongxuan Hua, Yameng Sun, Hong You, Wei Chen

Journal: Nature Communications

PubMed ID: 40830346

Doi: 10.1038/s41467-025-63006-z.

Products & Services: Protein Electrophoresis and Western

Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics

Authors: Martin Steger, Gisele Nishiguchi, Qiong Wu, Bjoern Schwalb, Bachuki Shashikadze, Kevin McGowan, Marisa Actis, Anup Aggarwal, Zhe Shi, Jeanine Price, Anand Mayasundari, Lei Yang, Anastasia H Bednarz, Sophie Machata, Tobias Graef, Denis Bartoschek, Vadim Demichev, Uli Ohmayer, Jun Yang, Henrik Daub, Zoran Rankovic

Journal: Nature Communications

PubMed ID: 40835825

Doi: 10.1038/s41467-025-62829-0.

Products & Services: Custom Vector Construction

Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons

Authors: Liangzhen Dong, Jiayu Wang, Qing Xia

Journal: Nature Communications

PubMed ID: 40846860

Doi: 10.1038/s41467-025-62981-7.

Products & Services: Gene Synthesis

Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction

Authors: Xinming Wang, Yiming Zhong, Bei Qian, Shixing Huang, Qiang Long, Haonan Zhang, Qiang Zhao, Xiaofeng Ye

Journal: Materials today, Bio

PubMed ID: 40893381

Doi: 10.1016/j.mtbio.2025.102205

Products & Services: Catalog IVT RNA products

A Novel Fluorescence Polarization Binding Assay for the Main Protease (M pro ) of SARS-CoV 2

Authors: Mackenzie K. Wyllie; Rayhan G. Biswas; Jyoti Vishwakarma; Morgan A. Esler; Joseph A. Rollie; Hideki Aihara; Reuben S. Harris; Daniel A. Harki

Journal: ACS pharmacology & translational science

PubMed ID: 41262570

Doi: 10.1021/acsptsci.5c00463

Identification of 14-3 3 Proteins as Binding Partners of TRP Channels

Authors: Nicol s Pe a-Vilches; Mariela Gonz lez-Avenda o; Nicole Soto-Garc a; Diego Maureira; Ian Silva; Javiera Avil s; El as Manr quez-Ben tez; Exequiel Medina; Oscar Cerda; Pablo Galaz-Davison; Ariela Vergara-Jaque

Journal: Journal of chemical information and modeling

PubMed ID: 41839059

Doi: 10.1021/acs.jcim.6c00092

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602