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Pyroptosis-responsive microspheres modulate the inflammatory microenvironment to retard osteoporosis in female mice

Authors: Shunyi Lu, Jie Cao, Zhuorun Song, Fei Gong, Peng Yang, Jun Ge, Yunfei He, Zhihui Han, Guanghui Hou, Zimin Zhang, Yuqi Yang, Yun Teng, Zengli Zhang, Jun Zou, Liang Cheng, Huilin Yang

Journal: Nature Communications

PubMed ID: 40885754

Doi: doi.org/10.1038/s41467-025-63456-5

Products & Services: Protein and Antibody Isolation

A Molecular Mechanism for the Reduction of the Cu Site in Lytic Polysaccharide Monooxygenases by Phenol Reductants

Authors: Langxing Liao, Jian Kuang, Peng Wu, Xianhang Sang, Heng Yin, Changlin Ti, Kingwang Zhang, Wei Peng, Lu Yu, Binju Wang

Journal: JACS Au

Doi: 10.1021/jacsau.5c00562

Products & Services: Gene Synthesis

AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides

Authors: Shuwen Jin, Zihan Zeng, Xiyan Xiong, Baicheng Huang, Li Tang, Hongsheng Wang, Xiao Ma, Xiaochun Tang, Guoqing Shao, Xingxu Huang, Feng Lin

Journal: Communications Biology

PubMed ID: 40447738

Doi: 10.1038/s42003-025-08282-7

Products & Services: Peptide Synthesis

Constitutive arrestin recruitment by orphan GPR52 via an atypical binding mode

Authors: Xi Lin, Xiaohu Wei, Ning Pu, Ling Wang, Zhibin Zhang, Cuixia Li, Yang Yue, Junlin Liu, Qiwen Tan, Qianqian Sun, Fei Xu

Journal: Cell Research

PubMed ID: 40813798

Doi: 10.1038/s41422-025-01165-w

Products & Services: Protein and Antibody Isolation

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602

Doi: 10.1038/s41467-025-62303-x.

Products & Services: Polyclonal Antibody Services

GTP hydrolysis triggers membrane remodeling by AMPH-1

Authors: Wei Gai https://orcid.org/0009-0005-5681-7380, Yuhang Wang https://orcid.org/0000-0002-8048-138X, Brianna Martin, Junjie Zhang https://orcid.org/0000-0002-7912-0819, Chavela M. Carr https://orcid.org/0009-0005-1292-1119, and Hays S. Rye

Journal: SCIENCE ADVANCES

PubMed ID: 40749062

Doi: 10.1126/sciadv.ads9443

Products & Services: Protein and Antibody Isolation

The EMC acts as a chaperone for membrane proteins

Authors: Carolin J Klose, Kevin M Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J Feige

Journal: Nature Communications

PubMed ID: 40753078

Doi: 10.1038/s41467-025-62109-x

Products & Services: Catalog Antibodies

IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes

Authors: Lei Bao, Christian F Guerrero Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Aadil Ahmed, N Ishii, T Hashimoto, Bethany E Perez White, Stefan Green, Kevin Kunstman, Nicole C Nowak, Connor Cole, Virgilia Macias, Maria Sverdlov, M Allen McAlexander, Christopher McCrae, Christopher D Nazaroff, Enno Schmidt, Kyle T Amber

Journal: Nature Communications

PubMed ID: 40769980

Doi: 10.1038/s41467-025-62495-2.

Products & Services: Antibody Modification and Purification Services

Self-splicing RNA circularization facilitated by intact group I and II introns

Authors: Yong Shen, Bohan Li, Lei Dong, Wei Tang, Jiwu Ren, Feng Chen, Wenjuan Zheng, Ying Yu, Lu Gao, Wensheng Wei

Journal: Nature Communications

PubMed ID: 40784880

Doi: 10.1038/s41467-025-62607-y.

Products & Services: Protein Electrophoresis and Western

Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair

Authors: Nourisson Antonin , Missoury Sophia, Lucas-Staat Soizick , Haouz Ahmed , Delarue Marc