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AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans
Authors: Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran
Journal: Science immunology
PubMed ID: 38579013
Doi: 10.1126/sciimmunol.adi8039
Products & Services: Gene Synthesis   
Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination
Authors: Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S Symington, Petr Cejka, Boris Pfander
Journal: Nature Communications
PubMed ID: 38570537
Doi: 10.1038/s41467-024-46951-z
Products & Services: Gene Synthesis   
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits
Authors: Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A Burger, Wei-Chiao Huang, Jonathan F Lovell, Danielle van Manen, Rogier W Sanders, Roland C Zahn, Hanneke Schuitemaker, Johannes P M Langedijk, Frank Wegmann
Journal: Nature Communications
PubMed ID: 38605096
Doi: 10.1038/s41467-024-47492-1
Products & Services: Codon Optimization   
Author Correction: Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae
Authors: San Hadži, Zala Živič, Matic Kovačič, Uroš Zavrtanik, Sarah Haesaerts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris
Journal: Nat Commun
PubMed ID: 38664458
Doi: 10.1038/s41467-024-47946-6
Products & Services: Custom Vector Construction   
Dual-responsive nanocarriers for efficient cytosolic protein delivery and CRISPR-Cas9 gene therapy of inflammatory skin disorders
Authors: Echuan Tan, Tao Wan, Qi Pan, Jianan Duan, Song Zhang, Ruijue Wang, Peng Gao, Jia Lv, Hui Wang, Dali Li, Yuan Ping, Yiyun Cheng
Journal: SCIENCE ADVANCES
PubMed ID: 38630829
Doi: 10.1126/sciadv.adl4336
A selective Fibroblast Growth Factor Receptor 1/2 PROTAC degrader with 1 antitumor activity
Authors: Ying Kong , Xinyue Zhao , Zhaofu Wang , Siqi Yuan , Sheng Chen , Shidi Lou , Shichao Ma , Yunfeng Li , Xinghao Wang , Yangfeng Ge , Guobin Li , Hongbing Yang , Mengxi Zhao , Dandan Li , Hailong Zhang , Wenfu Tan , Juan Wang
Journal: Molecular cancer therapeutics
PubMed ID: 38647531
Doi: 10.1158/1535-7163.MCT-23-0719
Products & Services: Gene Synthesis   
A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development
Authors: Zhijuan Hu 1, Liang Yang 2, Maolei Zhang 2, Haite Tang 2, Yile Huang 3, Yujie Su 4, Yingzhe Ding 3, Chong Li 2, Mengfei Wang 4, Yunhao Zhou 4, Qing Zhang 5, Liman Guo 5, Yue Wu 5, Qianqian Wang 6, Ning Liu 6, Haoran Kang 2, Yi Wu 2, Deyang Yao 2, Yukun Li 4, Zifeng Ruan 4, Hao Wang 2, Feixiang Bao 2, Guopan Liu 3, Junwei Wang 2, Yaofeng Wang 3, Wuming Wang 7, Gang Lu 7, Dajiang Qin 8, Duanqing Pei 9, Wai-Yee Chan 7, Xingguo Liu
Journal: Cell Metab
PubMed ID: 38703762
Doi: 10.1016/j.cmet.2024.04.012
Products & Services: Monoclonal Antibody Services   
A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma
Authors: Wei Zhu, Zhiming Zhang, Jinzhang Chen, Xiaolan Chen, Lei Huang, Xiaoyong Zhang, Xuan Huang, Na Ma, Weikang Xu, Xuan Yi, Xinyu Lu, Xin Fu, Siwei Li, Guoheng Mo, Yiyue Wang, Guosheng Yuan, Mengya Zang, Qi Li, Xiaotao Jiang, Yajing He, Sha Wu, Yukai He, Yongyin Li, Jinlin Hou
Journal: Signal Transduct Target Ther
PubMed ID: 38643203
Doi: 10.1038/s41392-024-01792-6
Products & Services: Gene Synthesis   
Dual mode of DDX3X as an ATP-dependent RNA helicase and ATP-independent nucleic acid chaperone
Authors: Yi-Ning He, Xiao-Rui Han, Dong Wang, Jia-Li Hou, Xi-Miao Hou
Journal: Biochem Biophys Res Commun
PubMed ID: 38669753
Doi: 10.1016/j.bbrc.2024.149964
Products & Services: DNA Sequencing   
Ferroptosis and HMGB2 induced calreticulin translocation required for immunogenic cell death are controlled by the nuclear exporter XPO1
Authors: Ian Blair, Jingqi Fan, Kevin Gillespie, Clementina Mesaros
Journal: Res Sq
PubMed ID: 38496553
Doi: 10.21203/rs.3.rs-4009459/v1
Products & Services: Molecular Biology Reagents   

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