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The Strica Homolog AaCASPS16 Is Involved in Apoptosis in the Yellow Fever Vector, Aedes albopictus.

PLoS One.. 2016-06; 
K Meng, X Li, S Wang, C Zhong, Z Yang, L Feng, Q Liu.
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Catalog Products ... s interval between each cycle. After centrifugation at 15,000 g for 20 min at 4°C, the supernatant was collected and then applied to 500 μL of Ni-NTA high-affinity resin (Genscript) in a gravity column. The resin was washed with ... Get A Quote

摘要

Caspases are a family of cysteine proteases playing essential roles during apoptosis. Seven caspases identified in Drosophila were Dronc, Dredd, Strica, Dcp-1, Decay, Drice and Damm. Among them, Strica is an insect-specific caspase containing a long serine- and threonine- rich prodomain, of which function is not yet well studied. Here we identified a homolog of strica from Aedes albopictus, named as Aacasps16. Aacasps16 encoded a protein containing a putative serine- and threonine-rich prodomain and a well conserved caspase catalytic domain. AaCASPS16 shared high identity with dipteran insects Strica homologs. Alignment showed that the closest relative of AaCASPS16 was Aedes aegypti AeCASPS16. The expression pr... More

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