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The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

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ORF cDNA Clones/MolecularCloud … com/ProdukteDB/produkte.asp?doi=486962) with human SH2B1 alpha splice form clones (wild-type, 67Cys, 150Arg, 175Ala, 343Met, 484Ala, 616Pro, 689Leu) under a CMV promoter (all clones were provided by Origene, mutation induction by Genscript, Piscataway, NJ, USA … Get A Quote

摘要

We aimed to determine the effect of human SH2B1 variants on leptin and insulin signaling， major regulators of energy homeostasis， on the RNA level.

关键词

Expression genome-wide，GWAS，IRS，JAK，Locus，SH2B1，
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