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MicroRNA-30c functions as a tumor suppressor via targeting SNAI1 in esophageal squamous cell carcinoma.

Biomed. Pharmacother.. 2018-02; 
MaTeng,ZhaoYe,LuQitong,LuYun,LiuZhiyong,XueTao,ShaoYong
Products/Services Used Details Operation
Gene Synthesis … 2.10. Plasmid construction and cell transduction. The 3′-UTR sequence of SNAI1 or a mutant sequence with the predicted target sites was inserted into the KpnI and SacI sites of pGL3 promoter vector (Genscript, Nanjing, China) … Get A Quote

摘要

Aberrant expression of miRNAs was involved in tumor initiation, progression and metastasis in multiple cancers. Many kinds of microRNAs in esophageal squamous cell carcinoma (ESCC) have been researched, whereas miR-30c has not been included.

关键词

EMT,ESCC,miR