至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Plant-expressed pyocins for control of Pseudomonas aeruginosa

PLoS ONE. 2017-01; 
PaškevičiusŠarūnas, StarkevičUrtė, MisiūnasAudrius, VitkauskienėAstra, GlebaYuri, RažanskienėAu
Products/Services Used Details Operation
PCR and Cloning … and L3 coding sequences (NCBI Reference Sequences ERY59288, ERZ09841.1, WP_003115311, CDG56231.1, ERX71449.1, and ERZ04935.1, respectively) optimized for expression in the host plant Nicotiana benthamiana were synthetized by GenScript (USA) and inserted … Get A Quote

摘要

The emergence, persistence and spread of antibiotic-resistant human pathogenic bacteria heralds a growing global health crisis. Drug-resistant strains of gram-negative bacteria, such as Pseudomonas aeruginosa, are especially dangerous and the medical and economic burden they impose underscore the critical need for finding new antimicrobials. Recent studies have demonstrated that plant-expressed bacteriocins of the colicins family can be efficient antibacterials against all major enteropathogenic strains of E. coli. We extended our studies of colicin-like bacteriocins to pyocins, which are produced by strains of P. aeruginosa for ecological advantage against other strains of the same species. Using a pla... More

关键词