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piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.

Prostate. 2019-03; 
HanRuitong, ZhangLing, GanWeidong, FuKai, JiangKe, DingJie, WuJiang, HanXiaodong, LiDon
Products/Services Used Details Operation
PCR and Cloning … China). Stem‐loop RT primer and primer pairs were purchased from Nanjing Genscript Biotechnology (Nanjing, China). Immobilon Western Chemiluminescent HRP Substrate was purchased from Millipore Corp (Billerica, MA) … Get A Quote

摘要

Microcystin-leucine arginine (MC-LR) could disrupt prostate development and cause prostate hyperplasia. But whether and how maternal and before-weaning MC-LR exposure causes prostate hyperplasia in male offspring by changing expression profile of P-element-induced wimpy (PIWI)-interacting RNAs (piRNAs) have not yet been reported.

关键词

P-element-induced wimpy-interacting RNAs,cell proliferation,male offspring,microcystin-leucine arginine,pros