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Molecular Mapping of the Binding Sites of a Nav1. 1 Activator

Aalborg University Publication Repository(vbn.aau.dk). 2018;

Héctor Botella

Products/Services Used	Details	Operation
PCR Cloning and Subcloning	A pcDNA3.1-sfGFP1-10 vector (from GenScript, fig. 54), with the GFP strands 1-10 downstream in the multiple cloning site(MCS) was digested with the same pair of restriction enzymes for each insert, to later have the cohesive ends ligated between the two.	Get A Quote

摘要

Schizophrenia constitutes one of the most complex psychiatricdiseases whose environmental and genetic etiology makedifficult to treat.The diverse pathologic targets implied, and an extreme genotypic variability in patients considerably reduce treatment efficacy. A continuous search for newer drugsis ongoing, as current pharmacological treatments fail to address broadcohorts of patients and, in the best of cases, only partly ameliorate the psychotic symptoms