至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Functional expression of a novel Kunitz type protease inhibitor from the human blood fluke Schistosoma mansoni.

Parasit Vectors. 2015; 
RanasingheShiwanthi L,FischerKatja,GobertGeoffrey N,McManusDona
Products/Services Used Details Operation
Biochemicals … Octa‐arginine (R8) was purchased from Genscript (Piscataway, NJ, USA); Bangs Bead coupling buffer (50 mM 2‐(N‐morpholino)ethanesulfonic acid, pH 52; 005% ProClin 300) and 1‐ethyl‐3‐(3‐dimethylaminopropyl) carbodiimide (EDAC) was purchased from 2B Scientific … Get A Quote

摘要

Schistosomes are able to survive for prolonged periods in the blood system, despite continuous contact with coagulatory factors and mediators of the host immune system. Protease inhibitors likely play a critical role in host immune modulation thereby promoting parasite survival in this extremely hostile environment. Even though Kunitz type serine protease inhibitors have been shown to play important physiological functions in a range of organisms these proteins are less well characterised in parasitic helminths.

关键词