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Effect of Superparamagnetic Iron Oxide Nanoparticles-Labeling on Mouse Embryonic Stem Cells.

Cell J. 2015;

ParsaHamed，ShamsasenjanKarim，MovassaghpourAliakbar，AkbarzadehParvin，Amoghli TabriziBahram，DehdilaniNima，LotfinegadParisa，SoleimanlooFarz

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摘要

Superparamagnetic iron oxide nanoparticles (SPIONs) have been used to label mammalian cells and to monitor their fate in vivo using magnetic resonance imaging (MRI). However， the effectiveness of phenotype of labeled cells by SPIONs is still a matter of question. The aim of this study was to investigate the efficiency and biological effects of labeled mouse embryonic stem cells (mESCs) using ferumoxide- protamine sulfate complex.