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Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.

J. Infect. Dis.. 2015;

LaingKerry J，RussellRonnie M，DongLichun，SchmidD Scott，SternMichael，MagaretAmalia，HaasJürgen G，JohnstonChristine，WaldAnna，KoelleDav

Products/Services Used	Details	Operation
ORF cDNA Clones/MolecularCloud	Peptides (13-mers, overlapping by 9 amino acids) were synthesized for VZV ORF9 and ORF18 (Genscript, Piscataway, New Jersey)	Get A Quote

摘要

The live， attenuated varicella vaccine strain (vOka) is the only licensed therapeutic vaccine. Boost of varicella zoster virus (VZV)-specific cellular immunity is a likely mechanism of action. We examined memory CD4(+) T-cell responses to each VZV protein at baseline and after zoster vaccination.