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The role of RFamide-related peptide 3 (RFRP3) in regulation of the neuroendocrine reproductive and growth axes of the boar.

Anim. Reprod. Sci.. 2015; 
ThorsonJennifer F,DesaulniersAmy T,LeeChanho,WhiteBrett R,FordJ Joe,LentsCl
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Biochemicals 0.9% saline and RFRP3 (Val-Pro-Asn-Leu-Pro-Gln-Arg- Phe-NH2; GenScript Inc. Get A Quote

摘要

RFamide-related peptide 3 (RFRP3) has been implicated in regulating reproduction and growth. This regulation appears to be dependent upon sex, species, physiological status, and developmental stage. The objective of the present study was to evaluate the effects of RFRP3 on circulating concentrations of luteinizing hormone (LH) and growth hormone (GH) in mature boars. The hypothesis was RFRP3 would reduce circulating concentrations of LH and increase concentrations of GH. Meishan boars (716.6±2.8 days of age; 125.0±12.4kg BW) were randomly assigned to treatment: saline (n=4) or RFRP3 (8.5mg; n=5). Plasma was collected at 15-min intervals during 3 periods: pre-treatment, treatment, and post-treatment.... More

关键词

Boar, Growth hormone,Luteinizing hormone,Neuroendocrinology,RFamide-related pepti