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microRNA-193a-5p inhibits migration of human HT-29 colon cancer cells via suppression of metastasis pathway.

J. Cell. Biochem.. 2018; 
ShirafkanNaghmeh,ShomaliNavid,KazemiTohid,ShanehbandiDariush,GhasabiMehri,BaghbaniElham,GanjiMaziar,KhazeVahid,MansooriBehzad,BaradaranBe
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Molecular Biology Tools … 2.2 RNA isolation and quantitative real‐time polymerase chain reaction. Primer sequences were designed by GenScript online primers designs tool (genescript.com), as shown in Table 1, and blasted using the Primer‐Blast on the NCBI website (ncbi.nim.nih.gov) … Get A Quote

摘要

Altered expression of microRNAs (miRNAs) is indicated strongly in colorectal cancer (CRC). This study aims to evaluate the inhibitory role of miR-193a-5p on epithelial-mesenchymal transition markers in CRC lines. The cellular effects and potential mechanisms of miR-193a-5p were also examined.

关键词

CXCR4,colorectal cancer,metastasis,miR-193a-5p,microRNA,vime