Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder， with increasing incidence worldwide but unknown etiology. 6-Gingerol (6-GIN)， a major dietary compound found in ginger rhizome， has immunomodulatory activity. However， its role in autoimmune diseases， as well as the underlying mechanisms， are unclear. In this study， it is evaluated if 6-GIN can effectively ameliorate the clinical disease severity of experimental autoimmune encephalomyelitis， an animal model of MS.
Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder， with increasing incidence worldwide but unknown etiology. 6-Gingerol (6-GIN)， a major dietary compound found in ginger rhizome， has immunomodulatory activity. However， its role in autoimmune diseases， as well as the underlying mechanisms， are unclear. In this study， it is evaluated if 6-GIN can effectively ameliorate the clinical disease severity of experimental autoimmune encephalomyelitis， an animal model of MS.
