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Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.

Gastroenterology. 2019;

KatshaAhmed，SouttoMohammed，SehdevVikas，PengDunfa，WashingtonM Kay，PiazueloM Blanca，TantawyMohammed N，ManningH Charles，LuPengcheng，ShyrYu，EcsedyJeffrey，BelkhiriAbbes，El-Rifai

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Catalog Antibody	… room temperature. Next, cells were incubated in a specific primary antibody against NF-κBp65 (GenScript, Piscataway, NJ) diluted in PBS (1:400) for 2 hours at room temperature. After washing 3 times with ice-cold PBS, cells w.	Get A Quote

摘要

Chronic inflammation contributes to the pathogenesis of gastric tumorigenesis. The aurora kinase A (AURKA) gene is frequently amplified and overexpressed in gastrointestinal cancers. We investigated the roles of AURKA in inflammation and gastric tumorigenesis.