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Association of miR-182 expression in amniotic fluid with intrauterine infection and brain injury in premature infants.

Exp Ther Med. 2018; 
Gao Fengchun,Jiang Xiaojuan,Li Qirong,Fan Ke
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Biochemicals , Beijing, China Sigma-Aldrich; Merck KGaA, Darmstadt, Germany GenScript, Jiangsu, China H&E, hematoxylin and eosin; CT, computed tomography; PCR, polymerase chain reaction. Get A Quote

摘要

Changes of micro-ribonucleic acid-182 (miR-182) level in cases of intrauterine infection were investigated to explore the association between miR-182 level change and brain injury in premature infants. A total of 257 preterm infants born in obstetrics department of Jinan Maternity and Child Care Hospital from February 2015 to February 2017 were enrolled in this study. These preterm infants were divided into infected group (n=113) and uninfected group (n=144) based on pathological diagnosis results. Quantitative polymerase chain reaction (qPCR) was employed to detect miR-182 level in amniotic fluid. Bregmatic sagittal and coronal plus lateral fontanel craniocerebral ultrasound, craniocerebral computed tomograp... More

关键词

CT,brain injury in premature infants,imaging diagnosis,intrauterine infection,miR