至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Evolutionary significance and regulated expression of Tdrd family genes in gynogenetic Japanese flounder (Paralichthys olivaceus).

Comp. Biochem. Physiol. Part D Genomics Proteomics. 2019; 
WangBo,WangHuizhen,SongHaofei,JinChaofan,PengMeiting,GaoChen,YangFan,DuXinxin,QiJie,ZhangQuanqi,Chen
Products/Services Used Details Operation
Protein Tools FGENESH program (Solovyev et al., 2006) was utilized to predict coding sequences from the genome assembly, and WoLF PSORT (https://www.genscript.com/psort/wolf_psort.html) were used to predict protein localization. Get A Quote

摘要

Tudor domain-containing proteins (TDRDs) are highly conserved among organisms and have a function in gonads to regulate gametogenesis and genome stability through the piwi-interacting RNA (piRNA) pathway. With diverse sexual development patterns in teleost species, the evolution and function of Tdrd genes among teleosts remain unclear. Here, we identified and characterized 12 Tdrd genes (PoTdrds) in Japanese flounder (Paralichthys olivaceus) which represents dramatic sexual dimorphic metrics and sex reversal during sex differentiation. Phylogenetic and comparative synteny indicated the gain and loss of Tdrd genes after teleost-specific whole-genome duplication (3R-WGD). Tdrd1, Tdrd5, Tdrd6 and Ecat8 wer... More

关键词

Gynogenesis,Paralichthys olivaceus,Piwi-interacting RNA,Spermatogenesis,Sub-functionalization,Whole-genome duplica