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Highly sensitive solution-gated graphene transistors for label-free DNA detection.

Biosens Bioelectron. 2019; 
Li S, Huang K, Fan Q, Yang S, Shen T, Mei T, Wang J, Wang X, Chang G, Li J.
Products/Services Used Details Operation
Custom DNA/RNA Oligos … the future use. The single layer graphene on copper foil was purchased from VIGON Technology Company. DNA oligo was purchased from GENSCRIPT BIO Company and stored at −20 °C for the future use. The sequence of … Get A Quote

摘要

Highly sensitive and low-cost DNA detection are in great desire owing to the significant role of DNA molecules in detecting genetic damage and errors for the diagnosis and treatment of multiple diseases. Traditional detections of DNA mainly rely on large-scale instrument, which requires the complicated detection process and high cost. Solution-gated electrochemical transistors are widely studied due to high sensitivity and low cost. Here, we exploit a graphene electrochemical transistor for the efficient and sensitive DNA detection. The probe DNA is modified on the gate electrode to detect the target DNA molecules. A novel method is introduced to modify the gate electrode with the probe DNA to detect the differ... More

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