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Genome-wide identification of histone methylation (H3K9me2) and acetylation (H4K12ac) marks in two ecotypes of switchgrass (Panicum virgatum L.).

BMC Genomics. 2019; 
Ayyappan V, Sripathi VR, Kalavacharla VK,, Saha MC, Thimmapuram J, Bhide KP, Fiedler E.
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Molecular Biology Tools … analysis The primers were designed using the TaqMan qPCR primer design tool (GenScript USA Inc, Piscataway, NJ), and the primer pairs used to amplify the ChIP-enriched regions are presented in Additional file 1: Table S1 … Get A Quote

摘要

Histone modifications play a significant role in the regulation of transcription and various biological processes, such as development and regeneration. Though a few genomic (including DNA methylation patterns) and transcriptomic studies are currently available in switchgrass, the genome-wide distribution of histone modifications has not yet been studied to help elucidate gene regulation and its application to switchgrass improvement.,This study provides a comprehensive epigenomic analyses of two contrasting switchgrass ecotypes, lowland (AP13) and upland (VS16), by employing chromatin immunoprecipitation sequencing (ChIP-Seq) with two histone marks (suppressive- H3K9me2 and active- H4K12ac). In this study, mos... More

关键词

And monolignols; ChIP-Seq; Differential binding; Epigenome; Histone modifications; Phenylpropanoid pathway; Switchgrass