至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Concomitant RAS, RET/PTC, or BRAF Mutations in Advanced Stage of Papillary Thyroid Carcinoma

Thyroid Cancer and Nodules. 2014-07; 
Minjing Zou, Essa Y. Baitei, Ali S. Alzahrani, Faisal S. BinHumaid, Dania Alkhafaji, Roua A. Al-Rijjal, Brian F. Meyer, and Yufei Shi
Products/Services Used Details Operation
Mutant Libraries … Cloning and expression of mutant KRAS S65N and NRAS S65C. The full-length KRAS and NRAS cDNA clones were obtained from GenScript (Piscataway, NJ) and cloned into pcDNA3.1 under the control of the CMV promoter (Invitrogen, Carlsbad, CA) … Get A Quote

摘要

RET/PTC rearrangement, RAS, and BRAF mutations are considered to be mutually exclusive in papillary thyroid carcinoma (PTC). However, although concomitant mutations of RET/PTC, RAS, or BRAF have been reported recently, their significance for tumor progression and survival remains unclear. We sought to examine the prognostic value of concomitant mutations in PTC.

关键词