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Hawthorn Extract Alleviates Atherosclerosis through Regulating Inflammation and Apoptosis Related Factors: An Experimental Study

Chin J Integr Med. 2018-12-01; 
Song-Zi Wang, Min Wu, Ke-Ji Chen, Yue Liu, Jing Sun, Zhuo Sun, He Ma, Long-Tao Liu
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Nucleic Acid Purification & Analysis … PrimerQuest/Home/Index. Online design tools also exist for TaqMan probes (https://www.genscript.com/ssl-bin/app/primer). 45. Alternatively, run 5 μL from each PCR reaction in a 3 % agarose gel to check specificity. 46. Many biotech … Get A Quote

摘要

objective: To determine the effects of hawthorn extract on serum lipid levels, pathological changes in aortic atherosclerosis plaque, inflammatory factors, and apoptosis-related protein and mRNA expression in apolipoprotein E gene knockout (ApoE) mice. methods: Thirty-six ApoE mice were fed with a high-fat diet starting at the age of 8 weeks. Mice were randomly divided into 3 groups by a random number table including model group, hawthorn extract group, and simvastatin group, 12 mice in each group. Twelve 8-week-old C57BL/6 mice were fed a basic diet and served as control. The mice in the control and model groups were administered 0.2 mL saline daily, the mice in the hawthorn extract and simvastatin groups were... More

关键词

apoptosis-related protein, atherosclerosis, hawthorn extract, inflflammation factors, unstable plaque