Products/Services Used | Details | Operation |
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Plasmid DNA Preparation> | … purchased from Invitrogen (Carlsbad, CA, USA);the green fluorescent protein (GFP)-CRNDE plasmid was from Genscript Biotech (Piscataway, NJ, USA);and has-miR-29b-3p miScriptmiRNAMimics was from Qiagen (Valencia, CA, USA), and was transfected into cells using … | Get A Quote |
The development and progression of colorectal cancer (CRC) involve changes in genetic and epigenetic levels of oncogenes and/or tumor suppressors. In spite of advances in understanding of the molecular mechanisms involved in CRC, the overall survival rate of CRC still remains relatively low. Thus, more research is needed to discover and investigate effective biomarkers and targets for diagnosing and treating CRC. The roles of long non-coding RNAs (lncRNAs) participating in various aspects of cell biology have been investigated and potentially contribute to tumor development. Our recent study also showed that CRNDE was among the top 20 upregulated genes in CRC clinical tissues compared to normal colorectal tissu... More