Products/Services Used | Details | Operation |
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GenParts™ DNA Fragments> | … provided to GenScript USA Inc. The human naïve phage library used by Genscript USA Inc. … Fragments were run on a 0.8% agarose gel and extracted using Monarch Gel Purification kit … | Get A Quote |
The dataset presented here contains quantitative binding scores of scFv-format antibodies against a SARS-CoV-2 target peptide collected via an AlphaSeq assay that can be used in the development and benchmarking of machine learning models. Starting from three seed sequences identified from a phage display campaign using a human naïve library, four sets of 29,900 antibodies were designed in silico by creating all k = 1 mutations and random k = 2 and k = 3 mutations throughout the complementary-determining regions (CDRs). Of the 119,600 designs, 104,972 were successfully built in to the AlphaSeq library and target binding was subsequently measured with 71,384 designs resulting in a predicted affinity ... More