Products/Services Used | Details | Operation |
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Catalog Peptides> | … Synthetic JB001–JB006 peptides were purchased from Schafer-N (Copenhagen, Denmark), and JB006-free and biotinylated JB006 peptides were purchased from GenScript with … | Get A Quote |
Many snake venom toxins cause local tissue damage in prey and victims, which constitutes an important pathology that is challenging to treat with existing antivenoms. One of the notorious toxins that causes such effects is myotoxin II present in the venom of the Central and Northern South American viper, . This Lys49 PLA homologue is devoid of enzymatic activity and causes myotoxicity by disrupting the cell membranes of muscle tissue. To improve envenoming therapy, novel approaches are needed, warranting the discovery and development of inhibitors that target key toxins that are currently difficult to neutralize. Here, we report the identification of a new peptide (JB006), discovered using phage display technol... More