Products/Services Used | Details | Operation |
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Plasmid DNA Preparation> | … CHGB plasmids and control plasmids were manufactured by Genscript (Nanjing, China) at transfection grade with endotoxin <25 EU/mg, and all plasmids were diluted in saline to a … | Get A Quote |
Peptides play important roles in regulating biological processes and form the basis of a multiplicity of therapeutic drugs. To date, only about 300 peptides in human have confirmed bioactivity, although tens of thousands have been reported in the literature. The majority of these are inactive degradation products of endogenous proteins and peptides, presenting a needle-in-a-haystack problem of identifying the most promising candidate peptides from large-scale peptidomics experiments to test for bioactivity. To address this challenge, we conducted a comprehensive analysis of the mammalian peptidome across seven tissues in four different mouse strains and used the data to train a machine learning model that predi... More