至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Gimap5 Inhibits Lung Cancer Growth by Interacting With M6PR

Front Oncol. 2021-09; 
Pei Dai, Zhongxiang Tang, Pinglang Ruan, Ousman Bajinka, Dan Liu, Yurong Tan
Products/Services Used Details Operation
Custom Vector Construction Furthermore, pcDNA3.1-Gimap5/3×Flag-EGFP and pcDNA3.1-Control were constructed by Genscript Company (Beijing, China) Get A Quote

摘要

unassigned: Several studies have demonstrated the impacts of GTPases of immunity-associated proteins (GIMAPs) on malignant cells. However, the mechanisms through which Gimap5 regulates lung cancer cells are yet to be thoroughly investigated in the literature. Our study aimed to investigate the function of Gimap5 in the development of lung cancer. unassigned: The expression levels of the GIMAP family were analyzed in lung cancer patients of various cancer databases and lung cancer cell lines. After the survival rates of the cells were analyzed, we constructed Gimap5 over-expressed lung cancer cell lines and assessed the effects of Gimap5 on cell migration, cell invasion, cell proliferation and the epithelial-mes... More

关键词

GIMAP5, M6PR, PADI4, lung cancer, potential biomarker, prognosis