至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Assessing the antigenicity of different VP3 regions of infectious bursal disease virus in chickens from South Brazil

BMC Vet Res. 2021-07; 
Ana Paula Gori Palka, Tatiana Reichert Assunção de Matos, Claudemir de Souza, Danilo Santos Eugênio, Marco Aurélio Krieger, Stenio Perdigão Fragoso, Daniela Parada Pavoni
Products/Services Used Details Operation
Bacterial Expression A VP3 sequence (GenBank accession number ABI52864.1) was codon-optimized for expression in E. coli and purchased from GenScript (New Jersey, USA) Get A Quote

摘要

background: Infectious bursal disease (IBD), also known as Gumboro disease, is a viral infection that causes mortality and immunosuppression in chickens (Gallus gallus). VP2 and VP3 are the major structural viral capsid components and are the most immunogenic proteins of IBD virus (IBDV). Reliable diagnostic tests using VP2 and VP3 produced in heterologous systems are important tools to control this infection. One advantage of an IBD diagnostic based on VP3, over those that use VP2, is that VP3 has linear epitopes, enabling its production in bacteria. results: We tested the suitability of recombinant VP3 (rVP3) as a diagnostic reagent in an enzyme-linked immunosorbent assay (ELISA). Compared with a commercial t... More

关键词

Antigenic regions, ELISA, Gumboro disease, Infectious bursal disease, VP3