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Cross-kingdom inhibition of bacterial virulence and communication by probiotic yeast metabolites

Microbiome. 2021-03; 
Orit Malka, Dorin Kalson, Karin Yaniv, Reut Shafir, Manikandan Rajendran, Oshrit Ben-David, Ariel Kushmaro, Michael M Meijler, Raz Jelinek
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PCR and Cloning 10% SDS, 50% Glycerol; GenScript, Piscataway, USA) for 5 min at 95 °C. Get A Quote

摘要

background: Probiotic milk-fermented microorganism mixtures (e.g., yogurt, kefir) are perceived as contributing to human health, and possibly capable of protecting against bacterial infections. Co-existence of probiotic microorganisms are likely maintained via complex biomolecular mechanisms, secreted metabolites mediating cell-cell communication, and other yet-unknown biochemical pathways. In particular, deciphering molecular mechanisms by which probiotic microorganisms inhibit proliferation of pathogenic bacteria would be highly important for understanding both the potential benefits of probiotic foods as well as maintenance of healthy gut microbiome. results: The microbiome of a unique milk-fermented microor... More

关键词

Biofilms, Kluyveromyces marxianus, Microbiome, Probiotic microorganisms, Quorum sensing, Tryptophol acetate, Vibrio cholerae