| Products/Services Used | Details | Operation |
|---|---|---|
| Plasmid DNA Preparation | A custom-designed plasmid for SAMD14 (NM_174920.3) cloned into pcDNA3.1(+)-C-eGFP vector which confers neomycin resistance to allow stable generation of transgenic cell-line and a GFP reporter gene for isolation of SAMD14 expressing cells was constructed according to manufacturer’s instruction (GenScript) | Get A Quote |
The relationship between serum uric acid (UA) levels and cancer risk remains controversial. Here, a two-sample Mendelian randomization analysis was performed to identify a causal effect of serum UA levels on cancer risk. Twenty-six single nucleotide polymorphisms strongly associated with serum UA levels were screened as genetic variants from large-scale meta-analysis data of a genome-wide association study of 110,347 European individuals. Genetic associations with eight common site-specific cancers were subsequently explored. A total of six Mendelian randomization methods were used to estimate the potential effect of serum UA levels on cancer risk, including random effects inverse variance weighting, fix effect... More
