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SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.

NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2020-10; 
Schubert K,Karousis ED,Jomaa A,Scaiola A,Echeverria B,Gurzeler LA,Leibundgut M,Thiel V,Mühlemann O,Ban N
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Plasmid DNA Preparation Plasmids encoding the WT Nsp1 sequence and the N-terminal domain replaced by the soluble domain of E. coli thioredoxin were ordered from GenScript Biotech.  Get A Quote

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