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SARS-CoV-2 Surveillance of Wild Mice and Rats in North American Cities

Ecohealth. 2024-05; 
Lisa K F Lee, Chelsea G Himsworth, Natalie Prystajecky, Antonia Dibernardo, L Robbin Lindsay, Theresa M Albers, Rajeev Dhawan, Ken Henderson, Guy Mulder, Harveen K Atwal, Imara Beattie, Bruce K Wobeser, Michael H Parsons, Kaylee A Byers
Products/Services Used Details Operation
Molecular Biology Reagents … Serologic testing of Nobuto strip eluates was performed at the National Microbiology Laboratory using the GenScript cPass™ SARS-CoV-2 Neutralization Antibody Detection Kit (Cat# … Get A Quote

摘要

From July 2020 to June 2021, 248 wild house mice (Mus musculus), deer mice (Peromyscus maniculatus), brown rats (Rattus norvegicus), and black rats (Rattus rattus) from Texas and Washington, USA, and British Columbia, Canada, were tested for SARS-CoV-2 exposure and infection. Two brown rats and 11 house mice were positive for neutralizing antibodies using a surrogate virus neutralization test, but negative or indeterminate with the Multiplexed Fluorometric ImmunoAssay COVID-Plex, which targets full-length spike and nuclear proteins. Oro-nasopharyngeal swabs and fecal samples tested negative by RT-qPCR, with an indeterminate fecal sample in one house mouse. Continued surveillance of SARS-CoV-2 in wild rodents is... More

关键词

Animals, wild, Cities, House mice, Public health, Rats, SARS-CoV-2, Serology