多肽修饰服务

多肽修饰服务

金斯瑞拥有先进的多肽合成能力，并提供超过300种修饰类型，满足您在不同研究领域中的需求。

• 氨基端修饰类型

  BSA conjugation on N terminal -NH2	KLH conjugation on N terminal -NH2	OVA conjugation on N terminal -NH2	Acetylation
  Biotin	Biotin-Ahx	5-FAM	5-FAM-Ahx
  6-FAM	6-FAM-Ahx	2-Abz	4-Abz
  Cy3	Cy5	Cy5.5	Cy7
  DABCYL	Dansyl	Dansyl-Ahx	FITC-Ahx
  FITC-PEG2	5-TMR	6-TMR	Rhodamine B
  MCA	3-Maleimide	6-Maleimide	SMCC
  Acryl	Alloc	Benzoyl	CBZ
  Fmoc	Br-Ac	Cl-Ac	Aminooxy
  DOTA	NOTA	1-Nap	2-Nap
  Succinylation	Glutaric acid	Butyric acid,C4	Hexanoic acid,C6
  Octanoic acid,C8	Nonanoic acid,C9	Decanoic acid,C10	Lauric acid,C12
  Myristic acid,C14	Palmitic acid,C16	Stearic acid,C18	Arachidic acid,C20
  L-Lactic acid	D-Lactic acid	Lipoic acid (contains both L-/D-type)	2-Mercaptoacetic acid
  2-Azidoacetic acid	4-Azidobutyric acid	6-Azidohexanoic acid	Propiolic acid
  5-Hexynoicacid	Trans-Cinnamic acid	Trans-Crotonic acid	DBCO
  Methyltetrazine	TCO

• 羧基端修饰类型

  Amidation	Alcohol
  AMC	Bzl
  Cysteamide	EDA-Biotin
  Ester (OEt)	Ester (OMe)
  Glu(EDANS)	Hydrazine
  MPAA	NHEt
  Nhisopen	NHMe
  TBzl	p-Nitroanilide
  Tyr (3-NO2)	BSA conjugation on C terminal -COOH
  KLH conjugation on C terminal -COOH	OVA conjugation on C terminal -COOH

• 特殊氨基酸类型
• 同位素标记类型

  {Arg(13C6,15N4)}

  {Ile(13C6,15N)}

  {Leu(13C6,15N)}

  {Lys(13C6,15N2)}

  {Phe(13C9,15N)}

  {Pro(13C5,15N)}

  {Val(13C5,15N)}

• 荧光修饰类型/FRET对

  2-Abz (N-Terminal)	FITC-Ahx (N-Terminal)
  4-Abz (N-Terminal)	FITC-PEG2 (N-Terminal)
  5-FAM (N-Terminal)	MCA (N-Terminal)
  5-FAM-Ahx (N-Terminal)	Rhodamine B (N-Terminal)
  6-FAM (N-Terminal)	AMC (C-Terminal)
  6-FAM-Ahx (N-Terminal)	{ACC} (7-Aminocoumarin-4-Acetic acid)
  5-TMR (N-Terminal)	MCA/Lys(DNP)
  6-TMR (N-Terminal)	2-Abz/Lys(DNP)
  Cy3 (N-Terminal)	4-Abz/Lys(DNP)
  Cy5 (N-Terminal)	2-Abz/Tyr(3-NO2)
  Cy5.5 (N-Terminal)	4-Abz/Tyr(3-NO2)
  Cy7 (N-Terminal)	DABCYL/Glu(EDANS)
  Dansyl (N-Terminal)	DABCYL/EDANS
  Dansyl-Ahx (N-Terminal)

• 多肽偶联类型

  BSA (-COOH of C terminal)

  BSA Conjugation on cysteine

  KLH (-NH2 of N terminal)

  KLH Conjugation on cysteine

  OVA (-COOH of C terminal)

  OVA (-NH2 of N terminal)

  OVA Conjugation on cysteine

• 其他修饰类型

  MAPS	PEGylation	Cyclic modifications	Disulfide Bridges	Other
  MAPS Asymmetric 2 branches (C-Terminal)	{PEG1} NH2-(PEG)1-CH2COOH	Head to tail amide cyclic	Random Disulfide Bridge	Dimer ( Inter-Disulfide bridge)
  MAPS Asymmetric 4 branches (C-Terminal)	{PEG1-propionic acid} NH2-PEG1-CH2CH2COOH	Amide cyclic (Side chain)	Mono Disulfide bridge
  MAPS Asymmetric 8 branches (C-Terminal)	{PEG2} NH2-(PEG)2-CH2COOH	Stapled peptide(S5/S5)	Double Disulfide bridge
  	{PEG3} NH2-(PEG)3-CH2CH2COOH	Stapled peptide(R8/S5)	Triple Disulfide Bridge
  	{PEG4} NH2-(PEG)4-CH2CH2COOH	Mono Thioether Bridge
  	{PEG5} NH2-(PEG)5-CH2CH2COOH	Thioester (C-terminal)
  	{PEG6} NH2-(PEG)6-CH2CH2COOH	Amide cyclic (Head to side chain)
  	{PEG8} NH2-(PEG)8-CH2CH2COOH	Amide cyclic (Side chain to tail)
  	{PEG11} NH2-(PEG)11-CH2COOH
  	{PEG12} NH2-(PEG)12-CH2CH2COOH

  分支肽修饰

  PEG修饰

  环化修饰