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TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans
Authors: Yisui Xia, Ryo Fujisawa, Tom D Deegan, Remi Sonneville, Karim P M Labib
Journal: EMBO J
PubMed ID: 34269473
Doi: 10.15252/embj.2021108053
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Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors
Authors: Chiara Brullo, Federica Rapetti, Sara Abbate, Tommaso Prosdocimi, Archimede Torretta, Marta Semrau, Matteo Massa, Silvana Alfei, Paola Storici, Emilio Parisini, Olga Bruno
Journal: Eur J Med Chem
PubMed ID: 34171658
Doi: 10.1016/j.ejmech.2021.113638
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Characterization of an Atypical Hsp70 Demonstrates Its Cytosolic-Nuclear Localization and Modulation by Quercetin and Methylene Blue
Authors: Adélle Burger, Paula Macucule-Tinga, Stephen John Bentley, Michael Hans Ludewig, Ndumiso Nhlakanipho Mhlongo, Addmore Shonhai, Aileen Boshoff
Journal: Int J Mol Sci
PubMed ID: 34202520
Doi: 10.3390/ijms22136776
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Development of a Mini-Replicon-Based Reverse-Genetics System for Rice Stripe Tenuivirus
Authors: Mingfeng Feng, Luyao Li, Ruixiang Cheng, Yulong Yuan, Yongxin Dong, Minglong Chen, Rong Guo, Min Yao, Yi Xu, Yijun Zhou, Jianxiang Wu, Xin Shun Ding, Xueping Zhou, Xiaorong Tao
Journal: J Virol
PubMed ID: 33952642
Doi: 10.1128/JVI.00589-21
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High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP
Authors: Hyun Tae Lee, Ui Beom Park, Tae Jun Jeong, Nahyeon Gu, Sang Hyung Lee, Yujin Kim, Yong-Seok Heo
Journal: Biochem Biophys Res Commun
PubMed ID: 34144500
Doi: 10.1016/j.bbrc.2021.06.030
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Canine Transforming Growth Factor-β Receptor 2-Ig: A Potential Candidate Biologic for Melanoma Treatment That Reverses Transforming Growth Factor-β1 Immunosuppression
Authors: Hiroto Takeuchi, Satoru Konnai, Naoya Maekawa, Satoshi Takagi, Hiroshi Ohta, Noboru Sasaki, Sangho Kim, Tomohiro Okagawa, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Journal: Front Vet Sci
PubMed ID: 34195245
Doi: 10.3389/fvets.2021.656715
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Focused peptide library screening as a route to a superior affinity ligand for antibody purification
Authors: Krištof Bozovičar, Barbara Jenko Bizjan, Anže Meden, Jernej Kovač, Tomaž Bratkovič
Journal: Sci Rep
PubMed ID: 34079028
Doi: 10.1038/s41598-021-91208-0
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An optimized and robust SARS-CoV-2 pseudovirus system for viral entry research
Authors: Peng Yang, Yang Yang, Yuming Wu, Cong Huang, Yanlei Ding, Xuejun Wang, Shengqi Wang
Journal: J Virol Methods
PubMed ID: 34182038
Doi: 10.1016/j.jviromet.2021.114221
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Production of the infant formula ingredient 1,3-olein-2-palmitin in Arabidopsis thaliana seeds
Authors: Harrie van Erp, Fiona M Bryant, Jose Martin-Moreno, Louise V Michaelson, Peter J Eastmond
Journal: Metab Eng
PubMed ID: 34091040
Doi: 10.1016/j.ymben.2021.05.009
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Oral Administration of Producing Interferon Type II, Enhances the Immune Response Against Bacterial Pathogens in Rainbow Trout
Authors: Alvaro Santibañez, Diego Paine, Mick Parra, Carlos Muñoz, Natalia Valdes, Claudia Zapata, Rodrigo Vargas, Alex Gonzalez, Mario Tello
Journal: Front Immunol
PubMed ID: 34248997
Doi: 10.3389/fimmu.2021.696803
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