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Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir
Authors: Ho Sing Lo, Kenrie Pui Yan Hui, Hei-Ming Lai, Xu He, Khadija Shahed Khan, Simranjeet Kaur, Junzhe Huang, Zhongqi Li, Anthony K N Chan, Hayley Hei-Yin Cheung, Ka-Chun Ng, John Chi Wang Ho, Yu Wai Chen, Bowen Ma, Peter Man-Hin Cheung, Donghyuk Shin, Kaidao Wang, Meng-Hsuan Lee, Barbara Selisko, Cecilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Kuen-Phon Wu, Po-Huang Liang, Ivan Dikic, Zhong Zuo, Francis K L Chan, David S C Hui, Vincent C T Mok, Kam-Bo Wong, Chris Ka Pun Mok, Ho Ko, Wei Shen Aik, Michael Chi Wai Chan, Wai-Lung Ng
Journal: ACS Cent Sci
PubMed ID: 34075346
Doi: 10.1021/acscentsci.0c01186
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A sugarcane mosaic virus vector for rapid in planta screening of proteins that inhibit the growth of insect herbivores
Authors: Seung Ho Chung, Mahdiyeh Bigham, Ryan R Lappe, Barry Chan, Ugrappa Nagalakshmi, Steven A Whitham, Savithramma P Dinesh-Kumar, Georg Jander
Journal: Plant Biotechnol J
PubMed ID: 33763921
Doi: 10.1111/pbi.13585
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Optimizing Granulocyte Colony-Stimulating Factor Transcript for Enhanced Expression in
Authors:
Journal: Front Bioeng Biotechnol
PubMed ID: 33768088
Doi: 10.3389/fbioe.2021.630367
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Development of Rice Stripe Tenuivirus Minireplicon Reverse Genetics Systems Suitable for Analyses of Viral Replication and Intercellular Movement
Authors: Xiaoyan Zhang, Kai Sun, Yan Liang, Shuo Wang, Kaili Wu, Zhenghe Li
Journal: Front Microbiol
PubMed ID: 33833749
Doi: 10.3389/fmicb.2021.655256
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Immunotherapy of prostate cancer using novel synthetic DNA vaccines targeting multiple tumor antigens
Authors: Devivasha Bordoloi, Peng Xiao, Hyeree Choi, Michelle Ho, Alfredo Perales-Puchalt, Makan Khoshnejad, J Joseph Kim, Laurent Humeau, Alagarsamy Srinivasan, David B Weiner, Kar Muthumani
Journal: Genes Cancer
PubMed ID: 33884106
Doi: 10.18632/genesandcancer.214
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Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes
Authors: Patrick Johé, Elmar Jaenicke, Hannes Neuweiler, Tanja Schirmeister, Christian Kersten, Ute A Hellmich
Journal: J Biol Chem
PubMed ID: 33745969
Doi: 10.1016/j.jbc.2021.100565
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A dual cohesin-dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome
Authors: Marlene Duarte, Aldino Viegas, Victor D Alves, José A M Prates, Luís M A Ferreira, Shabir Najmudin, Eurico J Cabrita, Ana Luísa Carvalho, Carlos M G A Fontes, Pedro Bule
Journal: J Biol Chem
PubMed ID: 33744293
Doi: 10.1016/j.jbc.2021.100552
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H, C, and N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)
Authors: Ying Wang, John Kirkpatrick, Susanne Zur Lage, Sophie M Korn, Konstantin Neißner, Harald Schwalbe, Andreas Schlundt, Teresa Carlomagno
Journal: Biomol NMR Assign
PubMed ID: 33770349
Doi: 10.1007/s12104-021-10019-6
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characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis
Authors: I Dewa Made Kresna, Luis Linares-Otoya, Tobias Milzarek, Elke R Duell, Mahsa Mir Mohseni, Ute Mettal, Gabriele M König, Tobias A M Gulder, Till F Schäberle
Journal: Org Biomol Chem
PubMed ID: 33629091
Doi: 10.1039/d0ob02372h
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Long-term correction of ornithine transcarbamylase deficiency in Spf-Ash mice with a translationally optimized AAV vector
Authors: De Sabbata G,Boisgerault F,Guarnaccia C,Iaconcig A,Bortolussi G,Collaud F,Ronzitti G,Sola MS,Vidal P,Rouillon J,Charles S,Nicastro E,D'Antiga L,Ilyinskii P,Mingozzi F,Kishimoto TK,Muro AF
Journal: Molecular therapy. Methods & clinical development
PubMed ID: 33473356
Doi: 10.1016/j.omtm.2020.11.005
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