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Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction
Authors: Bihuan Chen , Xiaonan Liu , Yina Wang , Jie Bai , Xiangyu Liu , Guisheng Xiang , Wei Liu , Xiaoxi Zhu , Jian Cheng , Lina Lu , Guanghui Zhang , Ge Zhang, Zongjie Dai, Shuhui Zi , Shengchao Yang, Huifeng Jiang
Journal: PLoS Biol .
PubMed ID: 37279234
Doi: 10.1371/journal.pbio.3002131
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Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases
Authors: Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas, He Xi, Edward Murray, Daphne Y Ma, Krista Getty, Rachel Fearns
Journal: Commun Biol
PubMed ID: 37337079
Doi: 10.1038/s42003-023-04990-0
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Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene
Authors: Lindsey M Vansandt, Marie-Charlotte Meinsohn, Philippe Godin, Nicholas Nagykery, Natalie Sicher, Motohiro Kano, Aki Kashiwagi, Maeva Chauvin, Hatice D Saatcioglu, Julie L Barnes, Amy G Miller, Amy K Thompson, Helen L Bateman, Elizabeth M Donelan, Raquel González, Jackie Newsom, Guangping Gao, Patricia K Donahoe, Dan Wang, William F Swanson, David Pépin
Journal: Nat Commun
PubMed ID: 37280258
Doi: 10.1038/s41467-023-38721-0
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Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation
Authors: Xiaoyun Yang , Jiaxu Wang, Simin Li , Xiaobing Li , Jingjing Gong , Zhenzhen Yan , Huan Zhou , Chen Wu , Xiuhua Liu
Journal: Nucleic Acids Res .
PubMed ID: 37334830
Doi: 10.1093/nar/gkad525
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In silico design and validation of a novel multi-epitope vaccine candidate against structural proteins of Chikungunya virus using comprehensive immunoinformatics analyses
Authors: Shirin Mahmoodi, Javad Zamani Amirzakaria, Abdolmajid Ghasemian
Journal: PLoS ONE
PubMed ID: 37146081
Doi: 10.1371/journal.pone.0285177
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An Aurora B-RPA signaling axis secures chromosome segregation fidelity
Authors: Poonam Roshan, Sahiti Kuppa, Jenna R Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R Tumala, Aparna Biswas, Brian Bothner, Edwin Antony, Sofia Origanti
Journal: Nat Commun
PubMed ID: 37230964
Doi: 10.1038/s41467-023-38711-2
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Small heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation
Authors: JooYeon Jhun, Jeonghyeon Moon, Ji Ye Kwon, Keun-Hyung Cho, Seang Yoon Lee, Hyun Sik Na, Mi-La Cho, Jun-Ki Min
Journal: Cell Commun Signal
PubMed ID: 37143079
Doi: 10.1186/s12964-023-01054-y
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Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9
Authors: Gregory M Martin, Monica L Fernández-Quintero, Wen-Hsin Lee, Tossapol Pholcharee, Lisa Eshun-Wilson, Klaus R Liedl, Marie Pancera, Robert A Seder, Ian A Wilson, Andrew B Ward
Journal: Nat Commun
PubMed ID: 37198165
Doi: 10.1038/s41467-023-38509-2
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A novel anti-membrane CD30 single-chain variable fragment discovered from the human phage library: A potential targeted immunotherapy
Authors: Thanida Chanpong, Watee Seesuay, Wararat Chiangjong, Piamsiri Jiramornimit, Sarinthip Preedagasamzin, Korakot Atjanasuppat, Bunyada Jittorntrum, Somsak Prasongtanakij, Supannikar Tawinwung, Sulada Pukiat, Chonticha Saisawang, Suparerk Borwornpinyo, Khanit Sa-Ngiamsuntorn, Wanpen Chaichumpa, Suradej Hongeng, Usanarat Anurathapan
Journal: PLoS ONE
PubMed ID: 37079526
Doi: 10.1371/journal.pone.0284708
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Allosteric role of the citrate synthase homology domain of ATP citrate lyase
Authors: Xuepeng Wei, Kollin Schultz, Hannah L Pepper, Emily Megill, Austin Vogt, Nathaniel W Snyder, Ronen Marmorstein
Journal: Nat Commun
PubMed ID: 37076498
Doi: 10.1038/s41467-023-37986-9
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