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Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling
Authors: Bo Yu, Shiyu Luo, Yuhan Ding, Zijie Gong, Ting Nie
Journal: AMB Express
PubMed ID: 36370155
Doi: 10.1186/s13568-022-01489-5
Products & Services: Codon Optimization   
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease
Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu
Journal: Angew Chem Int Ed Engl
PubMed ID: 36308706
Doi: 10.1002/anie.202212378
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A broadly protective vaccine against cutaneous human papillomaviruses
Authors: Filipe Colaco Mariz, Kathrin Balz, Manuela Dittrich, Yueru Zhang, Fan Yang, Xueer Zhao, Angelo Bolchi, Simone Ottonello, Martin Müller
Journal: npj Vaccines
PubMed ID: 36216845
Doi: 10.1038/s41541-022-00539-0
Products & Services: Codon Optimization   
Combating the SARS-CoV-2 Omicron (BA1) and BA2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Authors: Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang
Journal: Cell Discov
PubMed ID: 36207299
Doi: 10.1038/s41421-022-00463-6
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Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H αβ tetramer
Authors: Abhinandan V Murthy, Ramita Sulu, Andrey Lebedev, Antti M Salo, Kati Korhonen, Rajaram Venkatesan, Hongmin Tu, Ulrich Bergmann, Janne Jänis, Mikko Laitaoja, Lloyd W Ruddock, Johanna Myllyharju, M Kristian Koski, Rik K Wierenga
Journal: J Biol Chem
PubMed ID: 36265586
Doi: 10.1016/j.jbc.2022.102614
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Resistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma
Authors: Yingdan Wang, Yunping Ma, Yan Xu, Jiangyan Liu, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang, Fan Wu, Jinghe Huang
Journal: Emerg Microbes Infect
PubMed ID: 35001836
Doi: 10.1080/22221751.2022.2027219
Products & Services: Custom Vector Construction   Codon Optimization   
CD8+ T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination
Authors: Emily S Ford, Koshlan Mayer-Blackwell, Lichen Jing, Anton M Sholukh, Russell St Germain, Emily L Bossard, Hong Xie, Thomas H Pulliam, Saumya Jani, Stacy Selke, Carlissa J Burrow, Christopher L McClurkan, Anna Wald, Michael R Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S Robins, Rebecca Elyanow, Rachel M Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G Chapuis, Andrew Fiore-Gartland, David M Koelle
Journal: Res Sq
PubMed ID: 36263073
Doi: 10.21203/rs.3.rs-2146712/v1
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A tunable metabolic valve for precise growth control and increased product formation in Pseudomonas putida
Authors: Christos Batianis, Rik P van Rosmalen, Monika Major, Cheyenne van Ee, Alexandros Kasiotakis, Ruud A Weusthuis, Vitor A P Martins Dos Santos
Journal: Metab Eng
PubMed ID: 36244546
Doi: 10.1016/j.ymben.2022.10.002
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Observation of conformational changes that underlie the catalytic cycle of Xrn2
Authors: Jan H Overbeck, David Stelzig, Anna-Lisa Fuchs, Jan Philip Wurm, Remco Sprangers
Journal: Nature Chemical Biology
PubMed ID: 36008487
Doi: 10.1038/s41589-022-01111-6
Products & Services: Codon Optimization   Gene Synthesis   
Characterization of a GH5 endoxylanase from Penicillium funiculosum and its synergism with GH16 endo-1,3(4)-glucanase in saccharification of sugarcane bagasse
Authors: Olusola A Ogunyewo, Omoaruemike E Okereke, Sandeep Kumar, Syed Shams Yazdani
Journal: Sci Rep
PubMed ID: 36241677
Doi: 10.1038/s41598-022-21529-1
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