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Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses
Authors: Ruyu Wang, Guanglei Zhai, Guanghao Zhu, Mengge Wang, Xiaoyi Gong, Weidong Zhang, Guangbo Ge, Hongzhuan Chen, Lili Chen
Journal: Bioorg Chem
PubMed ID: 36395603
Doi: 10.1016/j.bioorg.2022.106264
Products & Services: Gene Synthesis   
Mammalian Target of Rapamycin Inhibition Decreases Angiotensin II-Induced Steroidogenesis in HAC15 Human Adrenocortical Carcinoma Cells
Authors: Yusuf Ali, Elise P Gomez-Sanchez, Celso E Gomez-Sanchez
Journal: Endocrinology
PubMed ID: 36320101
Doi: 10.1210/endocr/bqac185
Products & Services: Gene Synthesis   
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Authors: Karianne Fjeld, Anny Gravdal, Ranveig S Brekke, Jahedul Alam, Steven J Wilhelm, Khadija El Jellas, Helene N Pettersen, Jianguo Lin, Marie H Solheim, Solrun J Steine, Bente B Johansson, Pål R Njølstad, Caroline S Verbeke, Xunjun Xiao, Mark E Lowe, Anders Molven
Journal: Pancreatology
PubMed ID: 36379850
Doi: 10.1016/j.pan.2022.11.003
Products & Services: Gene Synthesis   
Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types
Authors: Madhuvanthi Kannan, Ganesh Vasan, Simon Haziza, Cheng Huang, Radosław Chrapkiewicz, Junjie Luo, Jessica A Cardin, Mark J Schnitzer, Vincent A Pieribone
Journal: Science
PubMed ID: 36378956
Doi: 10.1126/science.abm8797
Products & Services: Gene Synthesis   
synDNA-a Synthetic DNA Spike-in Method for Absolute Quantification of Shotgun Metagenomic Sequencing
Authors: Livia S Zaramela, Megan Tjuanta, Oriane Moyne, Maxwell Neal, Karsten Zengler
Journal: mSystems
PubMed ID: 36317886
Doi: 10.1128/msystems.00447-22
Products & Services: Gene Synthesis   
A basal actinopterygian melanocortin receptor: molecular and functional characterization of an Mc2r ortholog from the Senegal bichir (Polypterus senegalus).
Authors: Ciaran A Shaughnessy , Mary F Jensen , Robert M Dores
Journal: Gen Comp Endocrinol
PubMed ID: 35973587
Doi: 10.1016/j.ygcen.2022.114105
Products & Services: Gene Synthesis   
TARDBP promotes ovarian cancer progression by altering vascular endothelial growth factor splicing
Authors: Yutian He, Zhenbo OuYang, Wenwen Liu, Yu Chen, Qiushi Zhang
Journal: Oncogene
PubMed ID: 36369320
Doi: 10.1038/s41388-022-02539-9
Products & Services: Gene Synthesis   
Bordetella pertussis whole cell immunization protects against Pseudomonas aeruginosa infections
Authors: Catherine B Blackwood, Margalida Mateu-Borrás, Emel Sen-Kilic, Gage M Pyles, Sarah Jo Miller, Kelly L Weaver, William T Witt, Annalisa B Huckaby, Jason Kang, Courtney E Chandler, Robert K Ernst, F Heath Damron, Mariette Barbier
Journal: npj Vaccines
PubMed ID: 36357402
Doi: 10.1038/s41541-022-00562-1
Products & Services: Gene Synthesis   
A reversible cell penetrating peptide-cargo linkage allows dissection of cell penetrating peptide- and cargo-dependent effects on internalization and identifies new functionalities of putative endolytic peptides
Authors: Daniel P Morris, Lucy C Snipes, Stephanie A Hill, Michael M Woods, Maria M Mbugua, Lydia R Wade, Jonathan L McMurry
Journal: Front Pharmacol .
PubMed ID: 36479201
Doi: 10.3389/fphar.2022.1070464
Products & Services: Gene Synthesis   
Antibody and T Cell Immune Responses to SARS-CoV-2 Peptides in COVID-19 Convalescent Patients
Authors: Kristina V Kitaeva , Daria S Chulpanova , Margarita N Zhuravleva , Ivan Yu Filin , Ruslan M Deviatiiarov , Alyssa C Ballard-Reisch , Albert A Rizvanov , Valeriya V Solovyeva
Journal: Bioengineering (Basel) .
PubMed ID: 36354566
Doi: 10.3389/fmicb.2022.842232
Products & Services: Gene Synthesis   

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