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Structure/function studies on the activation motif of two non-mammalian Mrap1 orthologs, and observations on the phylogeny of Mrap1, including a novel characterization of an Mrap1 from the chondrostean fish, Polyodon spathula.

Authors: Robert M. Dores , Greer McKinley, Audrey Meyers, Morgan Martin and Ciaran A. Shaughnessy

Journal: Biomolecules

Doi: 10.3390/biom12111681

Products & Services: Gene Synthesis

Developmentally regulated mitochondrial biogenesis and cell death competence in maize pollen

Authors: Karen C Chamusco, May N Milazzo, Kanchan S Bhan, Terry L Kamps, Prestina Smith, Modupeoluwa Durojaiye, Cristina D Moreira, Maria Gallo, Christine D Chase

Journal: BMC Plant Biol

PubMed ID: 36316635

Doi: 10.1186/s12870-022-03897-y

Products & Services: Gene Synthesis

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Authors: Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Giacomo Frati, Tristan Felix, Anne Chalumeau, Letizia Fontana, Jeanne Martin, Cecile Masson, Megane Brusson, Giulia Maule, Marion Rosello, Carine Giovannangeli, Vincent Abramowski, Jean-Pierre de Villartay, Jean-Paul Concordet, Filippo Del Bene, Wassim El Nemer, Mario Amendola, Marina Cavazzana, Anna Cereseto, Oriana Romano, Annarita Miccio

Journal: Nat Commun

PubMed ID: 36333351

Doi: 10.1038/s41467-022-34493-1

Products & Services: Gene Synthesis

A switchable Cas12a enabling CRISPR-based direct histone deacetylase activity detection

Authors: Wenyuan Kang , Lin Liu , Peihang Yu , Tianyi Zhang , Chunyang Lei , Zhou Nie

Journal: Biosens Bioelectron

PubMed ID: 35700604

Doi: doi.org/10.1016/j.bios.2022.114468

Products & Services: Gene Synthesis

Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone

Authors: Yongrui Liu , Yue Li , Hongyu Bao , Yanhong Liu , Liu Chen , Hongda Huang

Journal: J Mol Biol

PubMed ID: 35870648

Doi: 10.1016/j.jmb.2022.167756

Products & Services: Gene Synthesis

Prostaglandin E synchronizes lunar-regulated beach spawning in grass puffers

Authors: Junfeng Chen, Yuma Katada, Kousuke Okimura, Taiki Yamaguchi, Ying-Jey Guh, Tomoya Nakayama, Michiyo Maruyama, Yuko Furukawa, Yusuke Nakane, Naoyuki Yamamoto, Yoshikatsu Sato, Hironori Ando, Asako Sugimura, Kazufumi Tabata, Ayato Sato, Takashi Yoshimura

Journal: Curr Biol

PubMed ID: 36306789

Doi: 10.1016/j.cub.2022.09.062

Products & Services: Gene Synthesis

Structure of the core human NADPH oxidase NOX2

Authors: Sigrid Noreng, Naruhisa Ota, Yonglian Sun, Hoangdung Ho, Matthew Johnson, Christopher P Arthur, Kellen Schneider, Isabelle Lehoux, Christopher W Davies, Kyle Mortara, Kit Wong, Dhaya Seshasayee, Matthieu Masureel, Jian Payandeh, Tangsheng Yi, James T Koerber

Journal: Nat Commun

PubMed ID: 36241643

Doi: 10.1038/s41467-022-33711-0

Products & Services: Gene Synthesis

Target RNA activates the protease activity of Craspase to confer antiviral defense

Authors: Xi Liu, Laixing Zhang, Hao Wang, Yu Xiu, Ling Huang, Zhengyu Gao, Ningning Li, Feixue Li, Weijia Xiong, Teng Gao, Yi Zhang, Maojun Yang, Yue Feng

Journal: Mol Cell

PubMed ID: 36306795

Doi: 10.1016/j.molcel.2022.10.007

Products & Services: Gene Synthesis

PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction

Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma

Journal: Biosens Bioelectron

PubMed ID: 35797934

Doi: 10.1016/j.bios.2022.114497

Products & Services: Gene Synthesis

Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

Authors: Qianying Lv, Xinli Han, Jiajia Ni, Qianqian Ma, Rufeng Dai, Jiaojiao Liu, Jialu Liu, Yihui Zhai, Qian Shen, Li Sun, Haimei Liu, Jia Rao, Hong Xu

Journal: Cell Death Dis

PubMed ID: 36229446

Doi: 10.1038/s41419-022-05313-7

Products & Services: Gene Synthesis

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