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Expression and functional study of DNA polymerases from Psychrobacillus sp. BL-248-WT-3 and FJAT-21963
Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yuanchen Mao , Yun He , Hui Tian
Journal: Front Microbiol
PubMed ID: 39633807
Doi: doi.org/10.3389/fmicb.2024.1501020
Products & Services: Gene Synthesis   
Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia
Authors: Jihong Ma , Zhaohui Wang , Danielle Mintzlaff , Huiping Zhang , Rashmi Ramakrishna , Eduardo Davila , Matthew T Witkowski , M Scott Lucia , Marc S Schwartz , Elizabeth A Pomfret , David W Mathes , Zhirui Wang
Journal: Blood
PubMed ID: 39561285
Doi: 10.1182/blood.2024025277
Products & Services: Gene Synthesis   
An Isopentenol Utilization Pathway-Based “Deuterium-Scanning“Method for Mechanistic Investigations of Terpene Cyclases
Authors: Shouqi Zhang, Kaibiao Wang,Yuanning Liu, Tao Wang, Yao Kong, Pengcheng Zhang, Bo Zhang, Min Yin, Guohui Pan, and Zhengren Xu
Journal: ACS catalysis
Doi: 10.1021/acscatal.4c05811
Products & Services: Gene Synthesis   
Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies
Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao
Journal: Nat Commun
PubMed ID: 39528513
Doi: 10.1038/s41467-024-54150-z
Products & Services: Recombinant Proteins   Gene Synthesis   
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA
Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu
Journal: Bioorg Med Chem
PubMed ID: 39580855
Doi: 10.1016/j.bmc.2024.118016
Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression
Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu
Journal: J Mol Biol
PubMed ID: 39427983
Doi: 10.1016/J.JMB.2024.168822
Products & Services: Gene Synthesis   
SARS-CoV-2 N protein coordinates viral particle assembly through multiple domains
Authors: Yuewen Han 1, Haiwu Zhou 1, Cong Liu 1, Weiwei Wang 1, Yali Qin 2, Mingzhou Chen
Journal: Journal of Virology
PubMed ID: 39412257
Doi: 10.1128/jvi.01036-24
Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168
Authors: Huasong Ai , Zebin Tong , Zhiheng Deng , Qiang Shi, Shixian Tao , Gaoge Sun, Jiawei Liang , Maoshen Sun , Xiangwei Wu , Qingyun Zheng , Lujun Liang , Hang Yin , Jia-Bin Li , Shuai Gao , Changlin Tian , Lei Liu , Man Pan
Journal: Nature Chemical Biology
PubMed ID: 39394267
Doi: doi.org/10.1038/s41589-024-01750-x
Products & Services: Gene Synthesis   PCR and Cloning   
Efficient circularization of protein-encoding RNAs via a novel cis-splicing system
Authors: Shaojun Qi , Huiming Wang , Guopeng Liu , Qianshan Qin , Peng Gao , Bo Ying
Journal: Nucleic Acids Research
PubMed ID: 39162233
Doi: 10.1093/nar/gkae711
Products & Services: Gene Synthesis   
Intein splicing efficiency and RadA levels can control the mode of archaeal DNA replication
Authors: Geraldy L S Liman , Christopher W Lennon , Jaylin L Mandley , Alina M Galyon , Kelly M Zatopek , Andrew F Gardner , Thomas J Santangelo
Journal: SCIENCE ADVANCES
PubMed ID: 39292776
Doi: 10.1126/sciadv.adp4995
Products & Services: Gene Synthesis   Mutagenesis Services   

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