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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies

Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao

Journal: Nat Commun

PubMed ID: 39528513

Doi: 10.1038/s41467-024-54150-z

Products & Services: Recombinant Proteins Gene Synthesis

Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression

Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu

Journal: J Mol Biol

PubMed ID: 39427983

Doi: 10.1016/J.JMB.2024.168822

Products & Services: Gene Synthesis

RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA

Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu

Journal: Bioorg Med Chem

PubMed ID: 39580855

Doi: 10.1016/j.bmc.2024.118016

Products & Services: Gene Synthesis Proteins, Expression, Isolation and Analysis

SARS-CoV-2 N protein coordinates viral particle assembly through multiple domains

Authors: Yuewen Han 1, Haiwu Zhou 1, Cong Liu 1, Weiwei Wang 1, Yali Qin 2, Mingzhou Chen

Journal: Journal of Virology

PubMed ID: 39412257

Doi: 10.1128/jvi.01036-24

Products & Services: Plasmids for SARS-CoV-2 Detection and Research Gene Synthesis

Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168

Authors: Huasong Ai , Zebin Tong , Zhiheng Deng , Qiang Shi, Shixian Tao , Gaoge Sun, Jiawei Liang , Maoshen Sun , Xiangwei Wu , Qingyun Zheng , Lujun Liang , Hang Yin , Jia-Bin Li , Shuai Gao , Changlin Tian , Lei Liu , Man Pan

Journal: Nature Chemical Biology

PubMed ID: 39394267

Doi: doi.org/10.1038/s41589-024-01750-x

Products & Services: Gene Synthesis PCR and Cloning

Efficient circularization of protein-encoding RNAs via a novel cis-splicing system

Authors: Shaojun Qi , Huiming Wang , Guopeng Liu , Qianshan Qin , Peng Gao , Bo Ying

Journal: Nucleic Acids Research

PubMed ID: 39162233

Doi: 10.1093/nar/gkae711

Products & Services: Gene Synthesis

Intein splicing efficiency and RadA levels can control the mode of archaeal DNA replication

Authors: Geraldy L S Liman , Christopher W Lennon , Jaylin L Mandley , Alina M Galyon , Kelly M Zatopek , Andrew F Gardner , Thomas J Santangelo

Journal: SCIENCE ADVANCES

PubMed ID: 39292776

Doi: 10.1126/sciadv.adp4995

Products & Services: Gene Synthesis Mutagenesis Services

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Authors: Jiacheng Deng,† , Xueyuan Li,† , Hao Yu,† , Lin Yang1, Ziru Wang1, Wenfeng Yi, Ying Liu, Wenyu Xiao, Hongyong Xiang, Zicong Xie, Dongmei Lv, Hongsheng Ouyang, Daxin Pang, * and Hongming Yuan

Journal: Nucleic Acids Research

PubMed ID: 39271120

Doi: doi.org/10.1093/nar/gkae800

Products & Services: Gene Synthesis

Crystal structure and nucleic acid binding mode of CPV NSP9: implications for viroplasm in Reovirales

Authors: Yeda Wang , Hangtian Guo , Yuhao Lu , Wanbin Yang , Tinghan Li , Xiaoyun Ji

Journal: Nucleic Acids Research

PubMed ID: 39287123

Doi: doi.org/10.1093/nar/gkae803

Products & Services: Gene Synthesis

Structural characterization of the (deoxy)hypusination in Trichomonas vaginalis questions the bifunctionality of deoxyhypusine synthase

Authors: Elżbieta Wątor, Piotr Wilk, Paweł Kochanowski, Przemysław Grudnik

Journal: FEBS J

Doi: doi.org/10.1111/febs.17207

Products & Services: Gene Synthesis

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