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Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases
Authors: Souad Diana Tork, Mădălina Elena Moisă, Lilla Cserepes, Alina Filip, Levente Csaba Nagy, Florin Dan Irimie, László Csaba Bencze
Journal: Sci Rep
PubMed ID: 35739148
Doi: 10.1038/s41598-022-14585-0
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Sequence-specific H, C and N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1
Authors: Kayleigh Walker, Lorna C Waters, Geoff Kelly, Frederick W Muskett, Mark D Carr
Journal: Biomol NMR Assign
PubMed ID: 35675028
Doi: 10.1007/s12104-022-10092-5
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Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition
Authors: Eric T Baldwin, Matthias Götte, Egor P Tchesnokov, Eddy Arnold, Margit Hagel, Charles Nichols, Pam Dossang, Marieke Lamers, Paul Wan, Stefan Steinbacher, Donna L Romero
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35771941
Doi: 10.1073/pnas.2200260119
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Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens
Authors: Uddipan Kar, Sara Khaleeq, Priyanka Garg, Madhuraj Bhat, Poorvi Reddy, Venkada Subramanian Vignesh, Aditya Upadhyaya, Mili Das, Ghadiyaram Chakshusmathi, Suman Pandey, Somnath Dutta, Raghavan Varadarajan
Journal: Front Immunol
PubMed ID: 35720346
Doi: 10.3389/fimmu.2022.890622
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Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
Authors: Mengya Zhao, Chuanbo Zhang, Haibin Wang, Shifan He, Wenyu Lu
Journal: Biotechnol Lett
PubMed ID: 35643816
Doi: 10.1007/s10529-022-03264-9
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Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain
Authors: Sucharita Sarkar, Brent Runge, Ryan W Russell, Kumar Tekwani Movellan, Daniel Calero, Somayeh Zeinalilathori, Caitlin M Quinn, Manman Lu, Guillermo Calero, Angela M Gronenborn, Tatyana Polenova
Journal: J Am Chem Soc
PubMed ID: 35638584
Doi: 10.1021/jacs.2c03320
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Structural basis for the synthesis of the core 1 structure by C1GalT1
Authors: Andrés Manuel González-Ramírez, Ana Sofia Grosso, Zhang Yang, Ismael Compañón, Helena Coelho, Yoshiki Narimatsu, Henrik Clausen, Filipa Marcelo, Francisco Corzana, Ramon Hurtado-Guerrero
Journal: Nat Commun
PubMed ID: 35504880
Doi: 10.1038/s41467-022-29833-0
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Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection
Authors: Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao, Guann-Yi Yu
Journal: Front Immunol
PubMed ID: 35585971
Doi: 10.3389/fimmu.2022.872047
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L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases
Authors: Patricia Amara, Claire Saragaglia, Jean-Marie Mouesca, Lydie Martin, Yvain Nicolet
Journal: Nat Commun
PubMed ID: 35477710
Doi: 10.1038/s41467-022-29980-4
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Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6
Authors: Y V Sheludko, I M Gerasymenko, F J Herrmann, H Warzecha
Journal: Transgenic Res
PubMed ID: 35416604
Doi: 10.1007/s11248-022-00305-x
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