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Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses
Authors: Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Mei Liu, Xing-Lou Yang, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, Zheng-Li Shi, Jinghe Huang
Journal: Cell Discov
PubMed ID: 35443747
Doi: 10.1038/s41421-022-00401-6
Products & Services: Codon Optimization   Proteins, Expression, Isolation and Analysis   
Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in
Authors: Mengxu Li, Jinlai Zhang, Qiuyan Bai, Lixia Fang, Hao Song, Yingxiu Cao
Journal: Front Microbiol
PubMed ID: 35547152
Doi: 10.3389/fmicb.2022.898884
Products & Services: Codon Optimization   
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
Authors: Lisa Merklinger, Johannes Bauer, Per A Pedersen, Rune Busk Damgaard, J Preben Morth
Journal: Life Sci Alliance
PubMed ID: 35459736
Doi: 10.26508/lsa.202101309
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Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu supplants entropically favoured Zn to form Cu clusters under physiological conditions
Authors: Matthew R Mehlenbacher, Rahma Elsiesy, Rabina Lakha, Rhiza Lyne E Villones, Marina Orman, Christina L Vizcarra, Gabriele Meloni, Dean E Wilcox, Rachel N Austin
Journal: Chem Sci
PubMed ID: 35655557
Doi: 10.1039/d2sc00676f
Products & Services: Codon Optimization   
TFPIisacoloniccryptreceptorforTcdBfromhypervirulentclade2C.difficile
Authors: Jianhua Luo , Qi Yang , Xiaofeng Zhang , Yuanyuan Zhang , Li Wan , Xiechao Zhan , Yao Zhou , Liuqing He , Danyang Li , Dazhi Jin , Ying Zhen , Jing Huang , Yanyan Li , Liang Tao
Journal: Cell
PubMed ID: 35303428
Doi: 10.1016/j.cell.2022.02.010
Products & Services: Codon Optimization   
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination
Authors: Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel-Zarandi, Mariam Iskilova, Miriam Barrios-Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc-André Langlois, Anne-Claude Gingras, Yves Durocher
Journal: Clin Transl Immunology
PubMed ID: 35356067
Doi: 10.1002/cti2.1380
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A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants
Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva
Journal: Nat Commun
PubMed ID: 35292635
Doi: 10.1038/s41467-022-28978-2
Products & Services: Codon Optimization   
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
Authors: Eva Mittler, Anna Z Wec, Janne Tynell, Pablo Guardado-Calvo, Julia Wigren-Byström, Laura C Polanco, Cecilia M O'Brien, Megan M Slough, Dafna M Abelson, Alexandra Serris, Mrunal Sakharkar, Gerard Pehau-Arnaudet, Russell R Bakken, James C Geoghegan, Rohit K Jangra, Markus Keller, Larry Zeitlin, Olli Vapalahti, Rainer G Ulrich, Zachary A Bornholdt, Clas Ahlm, Felix A Rey, John M Dye, Steven B Bradfute, Tomas Strandin, Andrew S Herbert, Mattias N E Forsell, Laura M Walker, Kartik Chandran
Journal: Sci Transl Med
PubMed ID: 35294259
Doi: 10.1126/scitranslmed.abl5399
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Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35149556
Doi: 10.1073/pnas.2119995119
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Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor
Authors: Haozhou Tan, Chunlong Ma, Jun Wang
Journal: Res Sq
PubMed ID: 35378761
Doi: 10.21203/rs.3.rs-1490282/v1
Products & Services: Codon Optimization   

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