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Extrusion pump ABCC1 was first linked with nonsyndromic hearing loss in humans by stepwise genetic analysis.
Authors: LiMeng，MeiLingyun，HeChufeng，ChenHongsheng，CaiXinzhang，LiuYalan，TianRunyi，TianQi，SongJian，JiangLu，LiuChang，WuHong，LiTaoxi，LiuJing，LiXiman，YiYifang，YanDenise，BlantonSusan H，HuZhengmao，LiuXuezhong，LiJiada，LingJie，Feng
Journal: Genet. Med.
PubMed ID: 31273342
Doi: 10.1038/s41436-019-0594-y
Products & Services: Mutagenesis Services   
MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy.
Authors: LiBo，DasguptaChiranjib，HuangLei，MengXianmei，Zhang
Journal: Cell. Mol. Immunol.
PubMed ID: 31300734
Doi: 10.1038/s41423-019-0257-6
Products & Services: Mutagenesis Services   
Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins
Authors: Thirawatananond P, McPherson RL,Malhi J, Nathan S, Lambrecht MJ, Brichacek M, Hergenrother PJ, Leung AKL, Gabelli SB.
Journal: Sci Rep.
PubMed ID: 30976021
Doi: 10.1038/s41598-019-39491-w.
Products & Services: Mutagenesis Services   
Complement C4 Prevents Viral Infection through Capsid Inactivation.
Authors: BottermannMaria，FossStian，CaddySarah L，CliftDean，van TienenLaurens M，VaysburdMarina，CruickshankJames，O'ConnellKevin，ClarkJessica，MayesKeith，HigginsonKatie，LodeHeidrun E，McAdamMartin B，SandlieInger，AndersenJan Terje，JamesL
Journal: Cell Host Microbe
PubMed ID: 30926239
Doi: 10.1016/j.chom.2019.02.016
Products & Services: Mutagenesis Services   
Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly
Authors: Eldirany SA, Ho M, Hinbest AJ, Lomakin IB, Bunick CG.
Journal: EMBO J
PubMed ID: 31036554
Doi: 10.15252/embj.2018100741
Products & Services: Gene Synthesis   Mutagenesis Services   
The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region.
Authors: TapkenDaniel, SteffensenThomas Bielefeldt, LethRasmus, KristensenLise Baadsgaard, GerbolaAlexander, GajhedeMichael, J?rgensenFlemming Steen, OlsenLars, KastrupJette Sand
Journal: Sci Rep
PubMed ID: 28387240
Doi: 10.1038/srep46145
Products & Services: Mutagenesis Services   
HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.
Authors: GirardRomain，DarsignyMathieu，JonesChristine，Maloum-RamiFa?za，GélinasYves，CarpentierAndré C，LaplanteMathieu，PerreaultNathalie，BoudreauFran?
Journal: Sci Rep
PubMed ID: 30862908
Doi: 10.1038/s41598-019-41061-z
Products & Services: Mutagenesis Services   
N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage， Secretion， and Stability.
Authors: StewartAshley N，TanStefanie Y，ClarkDavid J，ZhangHui，WongG Wil
Journal: Biochemistry
PubMed ID: 30566828
Doi: 10.1021/acs.biochem.8b00528
Products & Services: Mutagenesis Services   
Whole-exome sequencing identification of a novel splicing mutation of RUNX2 in a Chinese family with cleidocranial dysplasia.
Authors: ZhangTingting, WuJing, ZhaoXiaoxue, HouFeifei, MaTengfei, WangHuijuan, ZhangXu, ZhangXia
Journal: Arch. Oral Biol.
PubMed ID: 30798031
Doi: 10.1016/j.archoralbio.2019.02.005
Products & Services: Mutagenesis Services   
Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite
Authors: Bruning JM, Wang Y, Oltrabella F, Tian B, Kholodar SA, Liu H, Bhattacharya P, Guo S, Holton JM, Fletterick RJ, Jacobson MP, England PM.
Journal: Cell Chem Biol.
PubMed ID: 30853418
Doi: 10.1016/j.chembiol.2019.02.002
Products & Services: Mutagenesis Services   

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