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Combined Protein- and Ligand-Observed NMR Workflow to Screen Fragment Cocktails against Multiple Proteins: A Case Study Using Bromodomains

Authors: Johnson JA, Olson NM, Tooker MJ, Bur SK, Pomerantz WCK

Journal: Molecules (Basel, Switzerland)

PubMed ID: 32872491

Doi: 10.3390/molecules25173949

Products & Services: Mutant Libraries

Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2

Authors: Escande-Beillard N, Loh A, Saleem SN, Kanata K, Hashimoto Y, Altunoglu U, Metoska A, Grandjean J, Ng FM, Pomp O, Baburajendran N, Wong J, Hill J, Beillard E, Cozzone P, Zaki M, Kayserili H, Hamada H, Shiratori H, Reversade B

Journal: Neuron

PubMed ID: 32330411

Doi: 10.1016/j.neuron.2020.03.028

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Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress

Authors: Lina Wu, Qingzhu Wang, Feng Guo, Xiaojun Ma, Jiao Wang, Yanyan Zhao, Yushan Yan, Guijun Qin

Journal: J Cell Physiol

PubMed ID: 32691413

Doi: 10.1002/jcp.29951

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Dimethyl fumarate suppresses granulocyte macrophage colony-stimulating factor-producing Th1 cells in CNS neuroinflammation

Authors: Safavi F, Thome R, Li Z, Zhang GX, Rostami A

Journal: Neurology(R) neuroimmunology & neuroinflammation

PubMed ID: 32371548

Doi: 10.1212/NXI.0000000000000729

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Hsa_circ_0003998 promotes epithelial to mesenchymal transition of hepatocellular carcinoma by sponging miR-143-3p and PCBP1.

Authors: Song LN,Qiao GL,Yu J,Yang CM,Chen Y,Deng ZF,Song LH,Ma LJ,Yan HL

Journal: Journal of experimental & clinical cancer research : CR

PubMed ID: 32552766

Doi: 10.1186/s13046-020-01576-0

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Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape

Authors: J H Lorent , K R Levental , L Ganesan , G Rivera-Longsworth , E Sezgin , M Doktorova , E Lyman , I Levental

Journal: Nat Chem Biol

PubMed ID: 32367017

Doi: 10.1038/s41589-020-0529-6

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PRMT7 regulates RNA-binding capacity and protein stability in Leishmania parasites

Authors: Ferreira TR, Dowle AA, Parry E, Alves-Ferreira EVC, Hogg K, Kolokousi F, Larson TR, Plevin MJ, Cruz AK, Walrad PB

Journal: Nucleic Acids Research

PubMed ID: 32365184

Doi: 10.1093/nar/gkaa211

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Lowly expressed lncRNA PVT1 suppresses proliferation and advances apoptosis of glioma cells through up-regulating microRNA-128-1-5p and inhibiting PTBP1

Authors: Zheng Dahai, Chen Daliang, Lin Famu, Wan Xiang, Lu Lenian, Chen Jianmin, Xu Xiaobing

Journal: Brain Res Bull

PubMed ID: 32562719

Doi: 10.1016/j.brainresbull.2020.06.006

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Mutation in CATIP (C2orf62) causes oligoteratoasthenozoospermia by affecting actin dynamics

Authors: Arafat M,Harlev A,Har-Vardi I,Levitas E,Priel T,Gershoni M,Searby C,Sheffield VC,Lunenfeld E,Parvari R

Journal: Journal of medical genetics

PubMed ID: 32503832

Doi: 10.1136/jmedgenet-2019-106825

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Local and Systemic Effects of Brassinosteroid Perception in Developing Phloem.

Authors: Graeff M,Rana S,Marhava P,Moret B,Hardtke CS

Journal: Current biology : CB

PubMed ID: 32220322

Doi: 10.1016/j.cub.2020.02.029

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