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Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
Authors: Xiyuan Zhang, Hannah E Lou, Vishaka Gopalan, Zhihui Liu, Hilda M Jafarah, Haiyan Lei, Paige Jones, Carly M Sayers, Marielle E Yohe, Prashant Chittiboina, Brigitte C Widemann, Carol J Thiele, Michael C Kelly, Sridhar Hannenhalli, Jack F Shern
Journal: Cell Rep
PubMed ID: 36130486
Doi: 10.1016/j.celrep.2022.111363
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Proposal to Consider Chemical/Physical Microenvironment as a New Therapeutic Off-Target Approach
Authors: Alessandro Giuliani, Stefano Fais
Journal: Pharmaceutics
PubMed ID: 36297518
Doi: 10.3390/pharmaceutics14102084
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Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies
Authors: Cathrine Scheepers, Prudence Kgagudi, Nonkululeko Mzindle, Elin S Gray, Thandeka Moyo-Gwete, Bronwen E Lambson, Brent Oosthuysen, Batsirai Mabvakure, Nigel J Garrett, Salim S Abdool Karim, Lynn Morris, Penny L Moore
Journal: PLoS Pathog
PubMed ID: 36054228
Doi: 10.1371/journal.ppat.1010450
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Protein Stabilization by Alginate Binding and Suppression of Thermal Aggregation
Authors: Roger Chang, Martin Gruebele, Deborah E Leckband
Journal: Biomacromolecules
PubMed ID: 36054903
Doi: 10.1021/acs.biomac.2c00297
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Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA275
Authors: Qian Wang, Sho Iketani, Zhiteng Li, Yicheng Guo, Andre Yanchen Yeh, Michael Liu, Jian Yu, Zizhang Sheng, Yaoxing Huang, Lihong Liu, David D Ho
Journal: Cell Host Microbe
PubMed ID: 36108630
Doi: 10.1016/j.chom.2022.09.002
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Rational design of photosynthetic reaction center protein maquettes
Authors: Nathan M Ennist, Steven E Stayrook, P Leslie Dutton, Christopher C Moser
Journal: Front Mol Biosci
PubMed ID: 36213121
Doi: 10.3389/fmolb.2022.997295
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Evasion of neutralizing antibody responses by the SARS-CoV-2 BA275 variant
Authors: Panke Qu, John P Evans, Yi-Min Zheng, Claire Carlin, Linda J Saif, Eugene M Oltz, Kai Xu, Richard J Gumina, Shan-Lu Liu
Journal: Cell Host Microbe
PubMed ID: 36240764
Doi: 10.1016/j.chom.2022.09.015
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Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery
Authors: Ferdinando M Milazzo, Antonio Chaves-Sanjuan, Olga Minenkova, Daniela Santapaola, Anna M Anastasi, Gianfranco Battistuzzi, Caterina Chiapparino, Antonio Rosi, Emilio Merlo Pich, Claudio Albertoni, Emanuele Marra, Laura Luberto, Cécile Viollet, Luigi G Spagnoli, Anna Riccio, Antonio Rossi, M Gabriella Santoro, Federico Ballabio, Cristina Paissoni, Carlo Camilloni, Martino Bolognesi, Rita De Santis
Journal: Mol Ther
PubMed ID: 36114671
Doi: 10.1016/j.ymthe.2022.09.010
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Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
Authors: Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh Ichi Nagata
Journal: Brain
PubMed ID: 35851598
Doi: 10.1093/brain/awac106
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Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis
Authors: Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K Acharya
Journal: PLoS Biol
PubMed ID: 36170207
Doi: 10.1371/journal.pbio.3001599
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