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SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
Authors: Shreyasi Mukherjee, David M Luedeke, Leslie McCoy, Makiko Iwafuchi, Aaron M Zorn
Journal: Cell Rep
PubMed ID: 36001974
Doi: 10.1016/j.celrep.2022.111247
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Evolutionary adaptation of the protein folding pathway for secretability
Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou
Journal: EMBO J
PubMed ID: 36031863
Doi: 10.15252/embj.2022111344
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T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition
Authors: En Cai, Casey Beppler, John Eichorst, Kyle Marchuk, Scott W Eastman, Matthew F Krummel
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35914144
Doi: 10.1073/pnas.2203247119
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Efficacy of glucose transporter inhibitors for the treatment of ERRα-overexpressed colorectal cancer
Authors: Miao Zhao, Cairong Xu, Hui Zhu
Journal: Acta Biochim Pol
PubMed ID: 36026615
Doi: 10.18388/abp.2020_5852
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Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism
Authors: Carolina Gismene, Jorge Enrique Hernández González, Angela Rocio Niño Santisteban, Andrey Fabricio Ziem Nascimento, Lucas Dos Santos Cunha, Fábio Rogério de Moraes, Cristiano Luis Pinto de Oliveira, Caio C Oliveira, Paola Jocelan Scarin Provazzi, Pedro Geraldo Pascutti, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Journal: Int J Mol Sci
PubMed ID: 36077258
Doi: 10.3390/ijms23179857
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Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
Authors: Torleif Tollefsrud Gjølberg, Rahel Frick, Simone Mester, Stian Foss, Algirdas Grevys, Lene Støkken Høydahl, Øystein Kalsnes Jørstad, Tilman Schlothauer, Inger Sandlie, Morten C Moe, Jan Terje Andersen
Journal: Commun Biol
PubMed ID: 35982144
Doi: 10.1038/s42003-022-03787-x
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TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects
Authors: Shance Li, Chaoting Zhang, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu, Zheming Lu
Journal: Cancer Immunol Immunother
PubMed ID: 35988132
Doi: 10.1007/s00262-022-03275-5
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Immunoprophylaxis using polypeptide chimera vaccines plus adjuvant system promote Th1 response controlling the spleen parasitism in hamster model of visceral leishmaniasis
Authors: Miriã Rodrigues Gusmão, Thaís Lopes Valentim Di Paschoali Ostolin, Lívia Mendes Carvalho, Ana Flávia Pereira Costa, Gabriel José Lucas Moreira, Jamille Mirelle de Oliveira Cardoso, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt
Journal: Vaccine
PubMed ID: 35963820
Doi: 10.1016/j.vaccine.2022.08.005
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Second-Generation SuptoxR Strains for High-Level Recombinant Membrane Protein Production
Authors: Eleni Vasilopoulou, Artemis Giannakopoulou, Charalampos Kapsalis, Myrsini Michou, Aristeidis Michoglou-Sergiou, Fragiskos N Kolisis, Georgios Skretas
Journal: ACS Synth Biol
PubMed ID: 35922033
Doi: 10.1021/acssynbio.1c00598
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Influences of miR-378a-3p on the Pathogenesis of Allergic Rhinitis via GzmB-Mediated Inflammatory Reaction
Authors: Xuping Wang, Haiqing Zhang, Long Du, Lian Zhang
Journal: Evid Based Complement Alternat Med
PubMed ID: 36072399
Doi: 10.1155/2022/5926834
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